Yhhu 3792

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 462150

CAS#: unknown

Description: Yhhu 3792 is a notch signaling pathway activator. It enhances the self-renewal capability of NSCs and is active in vivo.


Chemical Structure

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Yhhu 3792
CAS# unknown

Theoretical Analysis

MedKoo Cat#: 462150
Name: Yhhu 3792
CAS#: unknown
Chemical Formula: C24H25ClN4O2
Exact Mass: 436.17
Molecular Weight: 436.940
Elemental Analysis: C, 65.97; H, 5.77; Cl, 8.11; N, 12.82; O, 7.32

Price and Availability

Size Price Availability Quantity
10mg USD 519 2 Weeks
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Synonym: Yhhu 3792

IUPAC/Chemical Name: 5-(3-Methoxyphenoxy)-N2-[4-(1-methylethyl)phenyl]-2,4-quinazolinediamine hydrochloride

InChi Key: WNNJMAWCEOKXEJ-UHFFFAOYSA-N

InChi Code: InChI=1S/C24H24N4O2.ClH/c1-15(2)16-10-12-17(13-11-16)26-24-27-20-8-5-9-21(22(20)23(25)28-24)30-19-7-4-6-18(14-19)29-3;/h4-15H,1-3H3,(H3,25,26,27,28);1H

SMILES Code: NC1=C2C(OC3=CC=CC(OC)=C3)=CC=CC2=NC(NC4=CC=C(C(C)C)C=C4)=N1.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 436.94 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Lu H, Cheng G, Hong F, Zhang L, Hu Y, Feng L. A Novel 2-Phenylamino-Quinazoline-Based Compound Expands the Neural Stem Cell Pool and Promotes the Hippocampal Neurogenesis and the Cognitive Ability of Adult Mice. Stem Cells. 2018;36(8):1273‐1285. doi:10.1002/stem.2843.