WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 574312
CAS#: 942195-19-9
Description: F-14329 is a tetramic acid fungal metabolite and a metal chelator. It chelates iron, copper, magnesium, zinc, and aluminum ions in cell-free assays.
MedKoo Cat#: 574312
Name: F-14329
CAS#: 942195-19-9
Chemical Formula: C21H27NO5
Exact Mass: 373.1889
Molecular Weight: 373.45
Elemental Analysis: C, 67.54; H, 7.29; N, 3.75; O, 21.42
Synonym: F-14329, Tolypocladenol B
IUPAC/Chemical Name: (3Z,5S)-3-[(2S,4S,6E)-1-hydroxy-2,4-dimethyl-6-octen-1-ylidene]-5-[(S)-hydroxy(4-hydroxyphenyl)methyl]-2,4-pyrrolidinedione
InChi Key: IWIISBMWNKBQQH-WZFGYRRTSA-N
InChi Code: InChI=1S/C21H27NO5/c1-4-5-6-12(2)11-13(3)18(24)16-20(26)17(22-21(16)27)19(25)14-7-9-15(23)10-8-14/h4-5,7-10,12-13,17,19,23-25H,6,11H2,1-3H3,(H,22,27)/b5-4+,18-16-/t12-,13-,17-,19-/m0/s1
SMILES Code: O=C([C@@]([C@@H](O)C1=CC=C(O)C=C1)([H])NC/2=O)C2=C([C@H](C[C@@H](C)C/C=C/C)C)\O
Appearance: Solid powder
Purity: >70% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 373.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1. Shang, Z., Li, L., Esposito, B.P., et al. New PKS-NRPS tetramic acids and pyridinone from an Australian marine-derived fungus, Chaunopycnis sp. Org. Biomol. Chem. 13(28), 7795-7802 (2015).
