Fellutanine A
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 462140

CAS#: 175414-35-4

Description: Fellutanine A is a diketopiperazine fungal metabolite that has been found in A. candidus.

Chemical Structure

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Fellutanine A
CAS# 175414-35-4
Instruction

Theoretical Analysis

MedKoo Cat#: 462140
Name: Fellutanine A
CAS#: 175414-35-4
Chemical Formula: C22H20N4O2
Exact Mass: 372.16
Molecular Weight: 372.428
Elemental Analysis: C, 70.95; H, 5.41; N, 15.04; O, 8.59

Price and Availability

Size Price Availability Quantity
1mg USD 329 2 Weeks
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Synonym: Fellutanine A

IUPAC/Chemical Name: (3R,6S)-3,6-bis(1H-indol-3-ylmethyl)-2,5-piperazinedione

InChi Key: DNHODRZUCGXYKU-BGYRXZFFSA-N

InChi Code: InChI=1S/C22H20N4O2/c27-21-19(9-13-11-23-17-7-3-1-5-15(13)17)25-22(28)20(26-21)10-14-12-24-18-8-4-2-6-16(14)18/h1-8,11-12,19-20,23-24H,9-10H2,(H,25,28)(H,26,27)/t19-,20+

SMILES Code: O=C(N[C@@H](CC1=CNC2=CC=CC=C21)C(N3)=O)[C@H]3CC4=CNC5=CC=CC=C54

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 372.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Shan T, Wang Y, Wang S, Xie Y, Cui Z, Wu C, Sun J, Wang J, Mao Z. A new p-terphenyl derivative from the insect-derived fungus Aspergillus candidus Bdf-2 and the synergistic effects of terphenyllin. PeerJ. 2020 Jan 2;8:e8221. doi: 10.7717/peerj.8221. PMID: 31915570; PMCID: PMC6942676.


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4: Ezekiel CN, Kraak B, Sandoval-Denis M, Sulyok M, Oyedele OA, Ayeni KI, Makinde OM, Akinyemi OM, Krska R, Crous PW, Houbraken J. Diversity and toxigenicity of fungi and description of Fusarium madaense sp. nov. from cereals, legumes and soils in north-central Nigeria. MycoKeys. 2020 Jun 8;67:95-124. doi: 10.3897/mycokeys.67.52716. PMID: 32565683; PMCID: PMC7295817.


5: Schulz D, Ohlendorf B, Zinecker H, Schmaljohann R, Imhoff JF. Eutypoids B-E produced by a Penicillium sp. strain from the North Sea. J Nat Prod. 2011 Jan 28;74(1):99-101. doi: 10.1021/np100633k. Epub 2010 Dec 3. PMID: 21126094.


6: de Carvalho AC, Lima CS, Torquato HFV, Domiciano AT, Silva SDC, de Abreu LM, Uemi M, Paredes-Gamero EJ, Vieira PC, Veiga TAM, de Medeiros LS. Chemodiversity and Anti-Leukemia Effect of Metabolites from Penicillium setosum CMLD 18. Metabolites. 2022 Dec 23;13(1):23. doi: 10.3390/metabo13010023. PMID: 36676948; PMCID: PMC9864219.


7: Singla R, Jaitak V. Multitargeted Molecular Docking Study of Natural-Derived Alkaloids on Breast Cancer Pathway Components. Curr Comput Aided Drug Des. 2017 Nov 10;13(4):294-302. doi: 10.2174/1573409913666170406144642. PMID: 28382865.


8: Vinokurova NG, Boĭchenko LV, Arinbasarov MU. Obrazovanie alkaloidov gribami roda Penicillium pri roste na zerne pshenitsy [Formation of alkaloids from Penicillium species fungi during growth on wheat kernels]. Prikl Biokhim Mikrobiol. 2003 Jul-Aug;39(4):457-60. Russian. PMID: 14520967.


9: Kozlovskiĭ AG, Vinokurova NG, Adanin VM. Diketodipiperazinovye alkaloidy gribov Penicillium piscarium Westling [Diketopiperazine alkaloids from the fungus Penicillium piscarium Westling]. Prikl Biokhim Mikrobiol. 2000 May- Jun;36(3):317-21. Russian. PMID: 10867952.