WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 462136

CAS#: 300851-67-6

Description: (±)-4-CMTB is a positive allosteric modulator of free fatty acid receptor 2 (FFAR2/GPR43). It selectively induces ERK1/2 phosphorylation in 293 T-REx cells expressing human FFAR2, but not FFAR1 or FFAR3.

Chemical Structure

CAS# 300851-67-6

Theoretical Analysis

MedKoo Cat#: 462136
Name: (±)-4-CMTB
CAS#: 300851-67-6
Chemical Formula: C14H15ClN2OS
Exact Mass: 294.0594
Molecular Weight: 294.797
Elemental Analysis: C, 57.04; H, 5.13; Cl, 12.03; N, 9.50; O, 5.43; S, 10.88

Price and Availability

Size Price Availability Quantity
5.0mg USD 275.0 2 Weeks
10.0mg USD 455.0 2 Weeks
25.0mg USD 830.0 2 Weeks
50.0mg USD 1315.0 2 Weeks
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Synonym: (±)-4-CMTB

IUPAC/Chemical Name: 4-chloro-α-(1-methylethyl)-N-2-thiazolyl-benzeneacetamide


InChi Code: InChI=1S/C14H15ClN2OS/c1-9(2)12(10-3-5-11(15)6-4-10)13(18)17-14-16-7-8-19-14/h3-9,12H,1-2H3,(H,16,17,18)


Appearance: Solid powder

Purity: >95% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 294.797 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Smith, N.J., Ward, R.J., Stoddart, L.A., et al. Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator. Mol. Pharmacol. 80(1), 163-173 (2011).