Kalashine

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 462100

CAS#: 76372-24-2

Description: Kalashine is a biomolecule obtained from the plant Berberis orthobotrys.


Chemical Structure

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Kalashine
CAS# 76372-24-2

Theoretical Analysis

MedKoo Cat#: 462100
Name: Kalashine
CAS#: 76372-24-2
Chemical Formula: C37H40N2O6
Exact Mass: 608.2886
Molecular Weight: 608.735
Elemental Analysis: C, 73.01; H, 6.62; N, 4.60; O, 15.77

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Kalashine; Khyberine 7'-methyl ether; DTXSID70997756

IUPAC/Chemical Name: 4H-Dibenzo(de,g)quinoline-1,10-diol, 5,6,6a,7-tetrahydro-2-methoxy-6-methyl-11-(4-(((1S)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)phenoxy)-, (6aR)-

InChi Key: FLWXJOMSSUAZEP-WUFINQPMSA-N

InChi Code: InChI=1S/C37H40N2O6/c1-38-14-12-22-18-30(42-3)31(43-4)20-26(22)27(38)16-21-6-9-25(10-7-21)45-37-29(40)11-8-23-17-28-33-24(13-15-39(28)2)19-32(44-5)36(41)35(33)34(23)37/h6-11,18-20,27-28,40-41H,12-17H2,1-5H3/t27-,28+/m0/s1

SMILES Code: OC1=C(OC)C=C2CCN(C)[C@]3([H])CC4=CC=C(O)C(OC5=CC=C(C[C@@H]6N(C)CCC7=C6C=C(OC)C(OC)=C7)C=C5)=C4C1=C23

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 608.735 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Anti-arthritic activity of aqueous-methanolic extract and various fractions of Berberis orthobotrys. Bien ex Aitch Alamgeer, Ambreen Malik Uttra, Umme Habiba Hasan BMC Complement Altern Med. 2017; 17: 371. Published online 2017 Jul 18. doi: 10.1186/s12906-017-1879-9 PMCID: PMC5516381

2: Phytopharmacology and Clinical Updates of Berberis Species Against Diabetes and Other Metabolic Diseases Tarun Belwal, Aarti Bisht, Hari Prasad Devkota, Hammad Ullah, Haroon Khan, Aseesh Pandey, Indra Dutt Bhatt, Javier Echeverría Front Pharmacol. 2020; 11: 41. Published online 2020 Feb 18. doi: 10.3389/fphar.2020.00041 PMCID: PMC7040237

3: A review on biological and chemical diversity in Berberis (Berberidaceae) Sharad Srivastava, Manjoosha Srivastava, Ankita Misra, Garima Pandey, AKS Rawat EXCLI J. 2015; 14: 247–267. Published online 2015 Feb 20. doi: 10.17179/excli2014-399 PMCID: PMC4614447