WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 462046
CAS#: 5560-78-1
Description: Teclozan, also known as WIN 13146, is an antiprotozoal agent. It is a dichloroacetamide.
MedKoo Cat#: 462046
Name: Teclozan
CAS#: 5560-78-1
Chemical Formula: C20H28Cl4N2O4
Exact Mass: 500.0803
Molecular Weight: 502.254
Elemental Analysis: C, 47.83; H, 5.62; Cl, 28.23; N, 5.58; O, 12.74
Synonym: Teclozan; Falmonox; Teclosine; Teclozine; NSC 107433; Teclosan; Teclosine; Win 13146; Win-13146; Win13146; Win-AM 13146;
IUPAC/Chemical Name: Acetamide, N,N'-(1,4-phenylenebis(methylene))bis(2,2-dichloro-N-(2-ethoxyethyl)-
InChi Key: MSJLJWCAEPENBL-UHFFFAOYSA-N
InChi Code: InChI=1S/C20H28Cl4N2O4/c1-3-29-11-9-25(19(27)17(21)22)13-15-5-7-16(8-6-15)14-26(10-12-30-4-2)20(28)18(23)24/h5-8,17-18H,3-4,9-14H2,1-2H3
SMILES Code: O=C(N(CC1=CC=C(CN(CCOCC)C(C(Cl)Cl)=O)C=C1)CCOCC)C(Cl)Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 502.254 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Antiamoebic drugs for treating amoebic colitis Maria Liza M Gonzales, Leonila F Dans, Juliet Sio‐Aguilar
Cochrane Database Syst Rev. 2019 Jan; 2019(1): CD006085. Published online 2019 Jan 9. doi: 10.1002/14651858.CD006085.pub3 PMCID: PMC6326239
2: Intestinal parasites. R Knight, M G Schultz, D W Hoskins, P D Marsden Gut. 1973 Feb; 14(2): 145–168. doi: 10.1136/gut.14.2.145 PMCID: PMC1412563
3: Comparative genomics identifies potential virulence factors in Clostridium tertium and C. paraputrificum Marina Muñoz, Daniel Restrepo-Montoya, Nitin Kumar, Gregorio Iraola, Giovanny Herrera, Dora I. Ríos Chaparro, Diana Díaz-Arévalo, Manuel A. Patarroyo, Trevor D. Lawley, Juan David Ramírez Virulence. 2019; 10(1): 657–676. Published online 2019 Jul 13. doi: 10.1080/21505594.2019.1637699 PMCID: PMC6629180
4: Parasite-related diarrhoeas WHO Scientific Working Group Bull World Health Organ. 1980; 58(6): 819–830.
PMCID: PMC2396014
5: Flavonoids as a Natural Treatment Against Entamoeba histolytica Moisés Martínez-Castillo, Judith Pacheco-Yepez, Nadia Flores-Huerta, Paula Guzmán-Téllez, Rosa A. Jarillo-Luna, Luz M. Cárdenas-Jaramillo, Rafael Campos-Rodríguez, Mineko Shibayama Front Cell Infect Microbiol. 2018; 8: 209. Published online 2018 Jun 22. doi: 10.3389/fcimb.2018.00209 PMCID: PMC6024094
6: Availability of essential medicines in primary health care of the Brazilian Unified Health System Renata Cristina Rezende Macedo do Nascimento, Juliana Álvares, Augusto Afonso Guerra, Junior, Isabel Cristina Gomes, Ediná Alves Costa, Silvana Nair Leite, Karen Sarmento Costa, Orlando Mario Soeiro, Ione Aquemi Guibu, Margô Gomes de Oliveira Karnikowski, Francisco de Assis Acurcio Rev Saude Publica. 2017; 51(Suppl 2): 10s.
Published online 2017 Sep 22. doi: 10.11606/S1518-8787.2017051007062 PMCID: PMC5676352
