Halicin | CAS#40045-50-9 | JNK Inhibitor

Halicin
featured

WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 534604

CAS#: 40045-50-9

Description: Halicin ia s novel inhibitor of the c-Jun N-Terminal kinase.

Chemical Structure

Halicin

CAS# 40045-50-9

Instruction

Theoretical Analysis

MedKoo Cat#: 534604
Name: Halicin
CAS#: 40045-50-9
Chemical Formula: C5H3N5O2S3
Exact Mass: 260.94
Molecular Weight: 261.292
Elemental Analysis: C, 22.98; H, 1.16; N, 26.80; O, 12.25; S, 36.81

Price and Availability

Size	Price	Availability
10mg	USD 320	2 Weeks
50mg	USD 850	2 Weeks
Bulk inquiry Welcome, Customer: Please do not inquire quote if your intended use is for a patient since our products are for research use and for chemical synthesis use, not for human use . For in-stock products, we listed price in the web page. You may inquire prices for which sizes were not listed. If no price is listed, this means the product is not in stock at the moment, which may be available via custom synthesis. For cost-effective reason, minimum order of 1g is requested (typically very expensive). The lead time is usually 2-4 months. Quote of less than 1g will not be provided. MedKoo may not offer quote for below reasons: (1) current available synthetic method appears to be extremely expensive which is obviously not affordable to most customers; (2) Key raw material to make the product is temporally not available; (3) DEA controlled substances; (4) the product is under patent protection in customer’s country.

Synonym: Halicin; SU-3327; SU 3327; SU3327

IUPAC/Chemical Name: 5-[(5-Ntro-1,3-thiazol-2-yl)sulfanyl]-1,3,4-thiadiazol-2-amine

InChi Key: NQQBNZBOOHHVQP-UHFFFAOYSA-N

InChi Code: InChI=1S/C5H3N5O2S3/c6-3-8-9-5(14-3)15-4-7-1-2(13-4)10(11)12/h1H,(H2,6,8)

SMILES Code: NC1=NN=C(SC2=NC=C([N+]([O-])=O)S2)S1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Instruction:

View handling instruction

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 261.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1

Volume 1

Concentration 2

Volume 2

1: Kutlu Z, Celik M, Bilen A, Halıcı Z, Yıldırım S, Karabulut S, Karakaya S, Bostanlık DF, Aydın P. Effects of umbelliferone isolated from the Ferulago pauciradiata Boiss. & Heldr. Plant on cecal ligation and puncture-induced sepsis model in rats. Biomed Pharmacother. 2020 May 4;127:110206. doi: 10.1016/j.biopha.2020.110206. Epub ahead of print. PMID: 32407990.

2: Polat G, Ugan RA, Cadirci E, Halici Z. Sepsis and Septic Shock: Current Treatment Strategies and New Approaches. Eurasian J Med. 2017 Feb;49(1):53-58. doi: 10.5152/eurasianjmed.2017.17062. PMID: 28416934; PMCID: PMC5389495.

3: Emet M, Ozcan H, Ozel L, Yayla M, Halici Z, Hacimuftuoglu A. A Review of Melatonin, Its Receptors and Drugs. Eurasian J Med. 2016 Jun;48(2):135-41. doi: 10.5152/eurasianjmed.2015.0267. PMID: 27551178; PMCID: PMC4970552.

4: Seyrek M, Halici Z, Yildiz O, Ulusoy HB. Interaction between dexmedetomidine and α-adrenergic receptors: emphasis on vascular actions. J Cardiothorac Vasc Anesth. 2011 Oct;25(5):856-62. doi: 10.1053/j.jvca.2011.06.006. Epub 2011 Sep 8. PMID: 21862350.

5: Suleyman H, Albayrak A, Bilici M, Cadirci E, Halici Z. Different mechanisms in formation and prevention of indomethacin-induced gastric ulcers. Inflammation. 2010 Aug;33(4):224-34. doi: 10.1007/s10753-009-9176-5. PMID: 20084447.

6: Suleyman H, Cadirci E, Albayrak A, Halici Z. Nimesulide is a selective COX-2 inhibitory, atypical non-steroidal anti-inflammatory drug. Curr Med Chem. 2008;15(3):278-83. doi: 10.2174/092986708783497247. PMID: 18333314.

Your view history

Halicin featured