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MedKoo CAT#: 462018

CAS#: 81733-79-1

Description: Dalargin is a endogenous opioid peptide leucine-encephalin. It exhibits a pronounced cytoprotective and regeneratory action and may take an important place in treating the internal organ diseases.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-07-10. Prices are subject to change without notice.

Dalargin is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, SDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 462018
Name: Dalargin
CAS#: 81733-79-1
Chemical Formula: C35H51N9O8
Exact Mass: 725.3861
Molecular Weight: 725.848
Elemental Analysis: C, 57.92; H, 7.08; N, 17.37; O, 17.63

Synonym: Dalargin; Tageflar; BRN 4287455; Tyrosyl-D-alanyl-glycyl-phenylalanyl-leucyl-arginine

IUPAC/Chemical Name: L-Arginine, N(sup 2)-(N-(N-(N-(L-tyrosyl-D-alanyl)glycyl)-L-phenylalanyl)-L-leucyl)-


InChi Code: InChI=1S/C35H51N9O8/c1-20(2)16-27(32(49)43-26(34(51)52)10-7-15-39-35(37)38)44-33(50)28(18-22-8-5-4-6-9-22)42-29(46)19-40-30(47)21(3)41-31(48)25(36)17-23-11-13-24(45)14-12-23/h4-6,8-9,11-14,20-21,25-28,45H,7,10,15-19,36H2,1-3H3,(H,40,47)(H,41,48)(H,42,46)(H,43,49)(H,44,50)(H,51,52)(H4,37,38,39)/t21-,25+,26+,27+,28+/m1/s1

SMILES Code: N=C(N)NCCC[C@@H](C(O)=O)NC([C@H](CC(C)C)NC([C@H](CC1=CC=CC=C1)NC(CNC([C@@H](C)NC([C@H](CC2=CC=C(O)C=C2)N)=O)=O)=O)=O)=O

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Activity profiles of dalargin and its analogues in μ-, δ- and κ-opioid receptor selective bioassays
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3: Influence of Chronobiology on the Nanoparticle-Mediated Drug Uptake into the Brain
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4: The Bactericidal Activity of Temporin Analogues Against Methicillin Resistant Staphylococcus aureus Anna Golda, Paulina Kosikowska-Adamus, Aleksandra Kret, Olena Babyak, Kinga Wójcik, Ewelina Dobosz, Jan Potempa, Adam Lesner, Joanna Koziel Int J Mol Sci. 2019 Oct; 20(19): 4761. Published online 2019 Sep 25. doi: 10.3390/ijms20194761 PMCID: PMC6801822

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6: Multifunctional Polymeric Nanoplatforms for Brain Diseases Diagnosis, Therapy and Theranostics Shahryar Shakeri, Milad Ashrafizadeh, Ali Zarrabi, Rasoul Roghanian, Elham Ghasemipour Afshar, Abbas Pardakhty, Reza Mohammadinejad, Anuj Kumar, Vijay Kumar Thakur Biomedicines. 2020 Jan; 8(1): 13. Published online 2020 Jan 13. doi: 10.3390/biomedicines8010013 PMCID: PMC7168063

7: Prospects for Creation of Cardioprotective and Antiarrhythmic Drugs Based on Opioid Receptor Agonists Leonid N Maslov, Igor Khaliulin, Peter R. Oeltgen, Natalia V. Naryzhnaya, Jian‐Ming Pei, Stephen A. Brown, Yury B. Lishmanov, James M. Downey Med Res Rev. 2016 Sep; 36(5): 871–923. Published online 2016 May 16. doi: 10.1002/med.21395 PMCID: PMC5082499

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