Balofloxacin dihydrate

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MedKoo CAT#: 461976

CAS#: 151060-21-8

Description: Balofloxacin dehydrate is a quinolone antibiotic, inhibiting the synthesis of bacterial DNA by interference with the enqyme DNA gyrase.


Price and Availability

Size Price Shipping out time Quantity
1g USD 280 2 Weeks
5g USD 568 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-10-26. Prices are subject to change without notice.

Balofloxacin dihydrate is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, SDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 461976
Name: Balofloxacin dihydrate
CAS#: 151060-21-8
Chemical Formula: C20H28FN3O6
Exact Mass: 425.1962
Molecular Weight: 425.4574
Elemental Analysis: C, 56.46; H, 6.63; F, 4.47; N, 9.88; O, 22.56


Synonym: Balofloxacin dihydrate; Balofloxacin hydrate

IUPAC/Chemical Name: (+/-)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-(methylamino)piperidino)-4-oxo-3-quinolinecarboxylic acid, dihydrate

InChi Key: WEGNYJXOCPJAPS-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H24FN3O4.2H2O/c1-22-11-4-3-7-23(9-11)17-15(21)8-13-16(19(17)28-2)24(12-5-6-12)10-14(18(13)25)20(26)27;;/h8,10-12,22H,3-7,9H2,1-2H3,(H,26,27);2*1H2

SMILES Code: O.O.CNC1CCCN(C1)c2c(F)cc3C(=O)C(=CN(C4CC4)c3c2OC)C(=O)O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Nakagawa T, Ishigai M, Kato M, Hayakawa N, Kinoshita H, Okutomi T, Ohkubo K, Okazaki A. Pharmacokinetics of the new fluoroquinolone balofloxacin in mice, rats, and dogs. Arzneimittelforschung. 1995 Jun;45(6):719-22. PubMed PMID:7646579.

2: Nakagawa T, Ishigai M, Hiramatsu Y, Kinoshita H, Ishitani Y, Ohkubo K, Okazaki A. Determination of the new fluoroquinolone balofloxacin and its metabolites in biological fluids by high performance liquid chromatography. Arzneimittelforschung. 1995 Jun;45(6):716-8. PubMed PMID: 7646578.