DSR-6434
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 408077

CAS#: 1059070-10-8

Description: DSR-6434 is a potent TLR7 agonist (EC50 = 7.2 nM). DSR-6434 activates several immune effector cells in vitro. DSR-6434 indicated an optimal balance between the agonistic potency and high water solubility. It also demonstrated a strong antitumor effect in vivo by intravenous administration in a tumor bearing mice model.


Price and Availability

Size Price Shipping out time Quantity
200mg USD 1850 2 Weeks
500mg USD 2650 2 Weeks
1g USD 3450 2 Weeks
2g USD 6450 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-04-03. Prices are subject to change without notice.

DSR-6434, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and SDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 408077
Name: DSR-6434
CAS#: 1059070-10-8
Chemical Formula: C19H28N8O2
Exact Mass: 400.2335
Molecular Weight: 400.487
Elemental Analysis: C, 56.98; H, 7.05; N, 27.98; O, 7.99


Synonym: DSR-6434; DSR 6434; DSR6434;

IUPAC/Chemical Name: 6-Amino-2-(butylamino)-9-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]methyl]-7,9-dihydro-8H-purin-8-one

InChi Key: SSZHESNDOMBSRV-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H28N8O2/c1-4-5-8-21-18-24-16(20)15-17(25-18)27(19(28)23-15)12-13-6-7-14(22-11-13)29-10-9-26(2)3/h6-7,11H,4-5,8-10,12H2,1-3H3,(H,23,28)(H3,20,21,24,25)

SMILES Code: O=C1NC2=C(N)N=C(NCCCC)N=C2N1CC3=CC=C(OCCN(C)C)N=C3


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001