RPN77612
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 408074

CAS#: 39777-61-2

Description: RPN77612 is a synthetic curcuminoid molecule with multiple bio-actvities, including (1) cytotoxic effect on HeLa, K562, MCF-​7 and MDA-​MB-​231 cancer cell lines; (2) ameliorating amyloid precursor protein (APP) and tau protein pathology and rescues cognitive deficits in neurodegenerative diseases; (3) inhibitor of transcription factor NF-​κB and activators of Nrf2 and uses thereof for treatment of neurological disoders and inflammatory diseases. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

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RPN77612
CAS# 39777-61-2
Instruction

Theoretical Analysis

MedKoo Cat#: 408074
Name: RPN77612
CAS#: 39777-61-2
Chemical Formula: C19H18O3
Exact Mass: 294.13
Molecular Weight: 294.350
Elemental Analysis: C, 77.53; H, 6.16; O, 16.31

Price and Availability

Size Price Availability Quantity
1g USD 2050 2 Weeks
2g USD 3450 2 Weeks
5g USD 5850 2 Weeks
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Synonym: RPN77612; RPN-77612; RPN 77612;

IUPAC/Chemical Name: (1E,4E)-1,5-Bis(2-methoxyphenyl)penta-1,4-dien-3-one

InChi Key: RCZMPCUUTSDNAJ-PHEQNACWSA-N

InChi Code: InChI=1S/C19H18O3/c1-21-18-9-5-3-7-15(18)11-13-17(20)14-12-16-8-4-6-10-19(16)22-2/h3-14H,1-2H3/b13-11+,14-12+

SMILES Code: O=C(/C=C/C1=CC=CC=C1OC)/C=C/C2=CC=CC=C2OC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
Soluble in DMSO 0.0 0.00

Preparing Stock Solutions

The following data is based on the product molecular weight 294.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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