WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 408074

CAS#: 39777-61-2

Description: RPN77612 is a synthetic curcuminoid molecule with multiple bio-actvities, including (1) cytotoxic effect on HeLa, K562, MCF-​7 and MDA-​MB-​231 cancer cell lines; (2) ameliorating amyloid precursor protein (APP) and tau protein pathology and rescues cognitive deficits in neurodegenerative diseases; (3) inhibitor of transcription factor NF-​κB and activators of Nrf2 and uses thereof for treatment of neurological disoders and inflammatory diseases. This product has not formal name. For the convenience of scientific communication, we named it by combining its Inchi key (3 letters from the first letter of each section) with the last 5 digit of its CAS#) according to MedKoo Chemical Nomenclature (https://www.medkoo.com/page/naming).

Chemical Structure

CAS# 39777-61-2

Theoretical Analysis

MedKoo Cat#: 408074
Name: RPN77612
CAS#: 39777-61-2
Chemical Formula: C19H18O3
Exact Mass: 294.1256
Molecular Weight: 294.35
Elemental Analysis: C, 77.53; H, 6.16; O, 16.31

Price and Availability

Size Price Availability Quantity
1.0g USD 2050.0 2 Weeks
2.0g USD 3450.0 2 Weeks
5.0g USD 5850.0 2 Weeks
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Synonym: RPN77612; RPN-77612; RPN 77612;

IUPAC/Chemical Name: (1E,4E)-1,5-Bis(2-methoxyphenyl)penta-1,4-dien-3-one


InChi Code: InChI=1S/C19H18O3/c1-21-18-9-5-3-7-15(18)11-13-17(20)14-12-16-8-4-6-10-19(16)22-2/h3-14H,1-2H3/b13-11+,14-12+


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 294.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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