Trolamine salicylate

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MedKoo CAT#: 533821

CAS#: 2174-16-5 (salt)

Description: Trolamine salicylate is the salt formed between triethanolamine and salicylic acid in a ratio of 1:1. It is used as an ingredient in sunscreens, analgesic creams, and cosmetics. The salicylic acid portion contributes to both the sun protection effect (by absorbing UVB radiation) and to the analgesic effect. The triethanolamine neutralizes the acidity of the salicylic acid. One benefit of this topical analgesic is that it has no odor, in contrast to other topical analgesics such as menthol.

Chemical Structure

Trolamine salicylate
CAS# 2174-16-5 (salt)

Theoretical Analysis

MedKoo Cat#: 533821
Name: Trolamine salicylate
CAS#: 2174-16-5 (salt)
Chemical Formula: C13H21NO6
Exact Mass: 287.14
Molecular Weight: 287.312
Elemental Analysis: C, 54.35; H, 7.37; N, 4.88; O, 33.41

Price and Availability

Size Price Availability Quantity
25g USD 350 2 Weeks
100g USD 750 2 Weeks
200g USD 1150 2 Weeks
500g USD 1650 2 Weeks
1kg USD 2650 2 Weeks
5kg USD 5650 2 Weeks
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Related CAS #: 10377-95-4 (ester), 2174-16-5 (salt),

Synonym: Trolamine salicylate; TEA-Salicylate; Triethanolamine salicylate; Mobisyl; Myoflex;

IUPAC/Chemical Name: 2-Hydroxybenzoic acid, compd. with 2,2',2''-nitrilotris(ethanol) (1:1)


InChi Code: InChI=1S/C7H6O3.C6H15NO3/c8-6-4-2-1-3-5(6)7(9)10;8-4-1-7(2-5-9)3-6-10/h1-4,8H,(H,9,10);8-10H,1-6H2


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Product Data:

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Soluble in DMSO 0.0 100.00

Preparing Stock Solutions

The following data is based on the product molecular weight 287.312000000000000000000000000000 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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