WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 533784

CAS#: 1321924-70-2

Description: VTX-27 is a novel potent and selective PKCθ inhibitor.

Chemical Structure

CAS# 1321924-70-2

Theoretical Analysis

MedKoo Cat#: 533784
Name: VTX-27
CAS#: 1321924-70-2
Chemical Formula: C20H24ClFN6O
Exact Mass: 418.1684
Molecular Weight: 418.9014
Elemental Analysis: C, 57.35; H, 5.78; Cl, 8.46; F, 4.54; N, 20.06; O, 3.82

Price and Availability

Size Price Availability Quantity
10.0mg USD 350.0 3 Weeks
25.0mg USD 750.0 3 Weeks
50.0mg USD 1350.0 3 Weeks
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Synonym: VTX-27; VTX 27; VTX27

IUPAC/Chemical Name: (2R)-2-[(2S)-4-[3-Chloro-5-fluoro-6-(2H-pyrazolo[3,4-b]pyridin-3-yl)pyridin-2-yl]piperazin-2-yl]-3-methylbutan-2-ol


InChi Code: InChI=1S/C20H24ClFN6O/c1-11(2)20(3,29)15-10-28(8-7-23-15)19-13(21)9-14(22)17(25-19)16-12-5-4-6-24-18(12)27-26-16/h4-6,9,11,15,23,29H,7-8,10H2,1-3H3,(H,24,26,27)/t15-,20+/m0/s1

SMILES Code: C[C@](O)([C@H]1NCCN(C2=NC(C3=C(C=CC=N4)C4=NN3)=C(F)C=C2Cl)C1)C(C)C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 418.9014 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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10.0mg / USD 350.0