Garcinol

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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 533624

CAS#: 78824-30-3

Description: Garcinol is a natural inhibitor of PCAF and p300 histone acetyltransferase (HAT) activity, enhancing the hsa-miR-181d/STAT3 and hsa-miR-181d/5A ratios in GBM cells.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-04-01. Prices are subject to change without notice.

Garcinol is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 533624
Name: Garcinol
CAS#: 78824-30-3
Chemical Formula: C38H50O6
Exact Mass: 602.3607
Molecular Weight: 602.812
Elemental Analysis: C, 75.71; H, 8.36; O, 15.92


Synonym: Garcinol

IUPAC/Chemical Name: (1S,3Z,5R,7R)-3-[(3,4-Dihydroxyphenyl)-hydroxymethylidene]-6,6-dimethyl-5,7-bis(3-methylbut-2-enyl)-1-[(2S)-5-methyl-2-prop-1-en-2-ylhex-4-enyl]bicyclo[3.3.1]nonane-2,4,9-trione

InChi Key: DTTONLKLWRTCAB-BZSUNBQASA-N

InChi Code: InChI=1S/C38H50O6/c1-22(2)11-13-27(25(7)8)20-37-21-28(15-12-23(3)4)36(9,10)38(35(37)44,18-17-24(5)6)34(43)31(33(37)42)32(41)26-14-16-29(39)30(40)19-26/h11-12,14,16-17,19,27-28,39-41H,7,13,15,18,20-21H2,1-6,8-10H3/b32-31-/t27-,28+,37+,38-/m0/s1

SMILES Code: O=C(/C1=C(C2=CC=C(O)C(O)=C2)/O)[C@@](C3=O)(C[C@@H](C(C)=C)C/C=C(C)\C)C[C@@H](C/C=C(C)\C)C(C)(C)[C@@]3(C/C=C(C)\C)C1=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001