Z36

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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 533468

CAS#: 1243148-19-7

Description: Z36 is a novel Bcl-xL inhibitor, upregulating the expression levels of FAM134B, LC3, and Atg9, inducing autophagy along with autophagic cell death, resulting in ER stress and the unfolded protein response (UPR).


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-08-12. Prices are subject to change without notice.

Z36 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 533468
Name: Z36
CAS#: 1243148-19-7
Chemical Formula: C23H24FN3O2
Exact Mass: 393.1853
Molecular Weight: 393.4624
Elemental Analysis: C, 70.21; H, 6.15; F, 4.83; N, 10.68; O, 8.13


Synonym: Z36; Z-36; Z 36

IUPAC/Chemical Name: (Z)-1-(3-(Dimethylamino)propyl)-5-fluoro-3-((5-methoxy-1H-indol-3-yl)methylene)indolin-2-one

InChi Key: CQNOITUXWKRVMB-JAIQZWGSSA-N

InChi Code: InChI=1S/C23H24FN3O2/c1-26(2)9-4-10-27-22-8-5-16(24)12-19(22)20(23(27)28)11-15-14-25-21-7-6-17(29-3)13-18(15)21/h5-8,11-14,25H,4,9-10H2,1-3H3/b20-11-

SMILES Code: O=C1N(CCCN(C)C)C2=C(C=C(F)C=C2)/C1=C/C3=CNC4=C3C=C(OC)C=C4


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001