WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 533374
CAS#: 544467-07-4
Description: 118-D-24 is an inhibitor of HSV-1 replication.
MedKoo Cat#: 533374
Name: 118-D-24
CAS#: 544467-07-4
Chemical Formula: C11H9N3O4
Exact Mass: 247.0593
Molecular Weight: 247.21
Elemental Analysis: C, 53.44; H, 3.67; N, 17.00; O, 25.89
This product is not in stock, which may be available by custom synthesis.
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Related CAS #: 544467-07-4
Synonym: 118-D-24; 118-D 24; 118-D24; 118D-24; 118D 24; 118D24;
IUPAC/Chemical Name: 4-[3-(Azidomethyl)phenyl]-2-hydroxy-4-oxo-2-butenoic acid
InChi Key: DWAUHOPROZDIJR-YHYXMXQVSA-N
InChi Code: InChI=1S/C11H9N3O4/c12-14-13-6-7-2-1-3-8(4-7)9(15)5-10(16)11(17)18/h1-5,16H,6H2,(H,17,18)/b10-5-
SMILES Code: O=C(O)/C(O)=C/C(C1=CC=CC(CN=[N+]=[N-])=C1)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 247.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
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4: McElrath MJ, Ballweber L, Terker A, Kreger A, Sakchalathorn P, Robinson B, Fialkow M, Lentz G, Hladik F. Ex vivo comparison of microbicide efficacies for preventing HIV-1 genomic integration in intraepithelial vaginal cells. Antimicrob Agents Chemother. 2010 Feb;54(2):763-72. doi: 10.1128/AAC.00891-09. Epub 2009 Nov 30. PMID: 19949052; PMCID: PMC2812173
