AAPK-25

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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 533356

CAS#: 2247919-28-2

Description: AAPK-25 is a novel selective dual inhibitor of Aurora/PLK, significantly inhibiting the development of the colon cancer growth and prolonging the median survival time.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-03-29. Prices are subject to change without notice.

AAPK-25 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 533356
Name: AAPK-25
CAS#: 2247919-28-2
Chemical Formula: C30H35ClN4O2
Exact Mass: 518.2449
Molecular Weight: 519.086
Elemental Analysis: C, 69.42; H, 6.80; Cl, 6.83; N, 10.79; O, 6.16


Synonym: AAPK-25; AAPK 25; AAPK-5

IUPAC/Chemical Name: 4-((6-Chloro-2-methoxyacridin-9-yl)methyl)-2-((4-(2-(dimethylamino)ethyl)piperazin-1-yl)methyl)phenol

InChi Key: FOMOXWWUGIIVIV-UHFFFAOYSA-N

InChi Code: InChI=1S/C30H35ClN4O2/c1-33(2)10-11-34-12-14-35(15-13-34)20-22-16-21(4-9-30(22)36)17-26-25-7-5-23(31)18-29(25)32-28-8-6-24(37-3)19-27(26)28/h4-9,16,18-19,36H,10-15,17,20H2,1-3H3

SMILES Code: OC1=CC=C(CC2=C(C=C(OC)C=C3)C3=NC4=CC(Cl)=CC=C42)C=C1CN5CCN(CCN(C)C)CC5


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001