Vilangine

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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 585376

CAS#: 4370-68-7

Description: Vilangine has hypoglycemic activity.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-02-28. Prices are subject to change without notice.

Vilangine is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 585376
Name: Vilangine
CAS#: 4370-68-7
Chemical Formula: C35H52O8
Exact Mass: 600.3662
Molecular Weight: 600.793
Elemental Analysis: C, 69.97; H, 8.72; O, 21.30


Synonym: Vilangine; Vilangin

IUPAC/Chemical Name: 2-[(2,5-dihydroxy-3,6-dioxo-4-undecylcyclohexa-1,4-dien-1-yl)methyl]-3,6-dihydroxy-5-undecylcyclohexa-2,5-diene-1,4-dione

InChi Key: SSBANIVTGNXXSJ-UHFFFAOYSA-N

InChi Code: InChI=1S/C35H52O8/c1-3-5-7-9-11-13-15-17-19-21-24-28(36)32(40)26(33(41)29(24)37)23-27-34(42)30(38)25(31(39)35(27)43)22-20-18-16-14-12-10-8-6-4-2/h36,38,41,43H,3-23H2,1-2H3

SMILES Code: O=C1C(CC2=C(O)C(C(CCCCCCCCCCC)=C(O)C2=O)=O)=C(O)C(C(CCCCCCCCCCC)=C1O)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Stalin A, Irudayaraj SS, Gandhi GR, Balakrishna K, Ignacimuthu S, Al-Dhabi NA. Hypoglycemic activity of 6-bromoembelin and vilangin in high-fat diet fed-streptozotocin-induced type 2 diabetic rats and molecular docking studies. Life Sci. 2016 May 15;153:100-17. doi: 10.1016/j.lfs.2016.04.016. Epub 2016 Apr 26. PubMed PMID: 27091376.

2: Narayanaswamy R, Shymatak M, Chatterjee S, Wai LK, Arumugam G. Inhibition of Angiogenesis and Nitric Oxide Synthase (NOS), by Embelin & Vilangin Using in vitro, in vivo & in Silico Studies. Adv Pharm Bull. 2014 Dec;4(Suppl 2):543-8. doi: 10.5681/apb.2014.080. Epub 2014 Dec 31. PubMed PMID: 25671187; PubMed Central PMCID: PMC4312403.

3: Durg S, Veerapur VP, Neelima S, Dhadde SB. Antidiabetic activity of Embelia ribes, embelin and its derivatives: A systematic review and meta-analysis. Biomed Pharmacother. 2017 Feb;86:195-204. doi: 10.1016/j.biopha.2016.12.001. Epub 2016 Dec 13. Review. PubMed PMID: 27984799.

4: Dallacker F, Löhnert G. [Derivatives of methylenedioxybenzene. 35. A novel synthesis of 3,6 dihydroxy-2-ethyl-1,4-benzoquinone, embelin, vilangin, rapanone, dihydromaesaquinone, bhogatin, spinulosin and oosporein]. Chem Ber. 1972;105(2):614-24. German. PubMed PMID: 4645596.

5: Swamy RN, Gnanamani A, Shanmugasamy S, Gopal RK, Mandal AB. Bioinformatics in crosslinking chemistry of collagen with selective cross linkers. BMC Res Notes. 2011 Oct 12;4:399. doi: 10.1186/1756-0500-4-399. PubMed PMID: 21989371; PubMed Central PMCID: PMC3213054.