WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 533309


Description: UCK2-IN-135546734 is a novel non-competitive UCK2 inhibitor, suppressing nucleoside salvage in cells both in the presence and absence of DHODH inhibitors.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 533309
Name: UCK2-IN-135546734
Chemical Formula: C23H22FN5O2S
Exact Mass: 451.1478
Molecular Weight: 451.5204
Elemental Analysis: C, 61.18; H, 4.91; F, 4.21; N, 15.51; O, 7.09; S, 7.10

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: UCK2-IN-135546734

IUPAC/Chemical Name: N-(3,5-Dimethylphenyl)-2-(((6-(4-fluorobenzyl)-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)thio)acetamide


InChi Code: InChI=1S/C23H22FN5O2S/c1-14-7-15(2)9-18(8-14)26-21(30)12-32-13-29-22-19(11-25-29)23(31)28-20(27-22)10-16-3-5-17(24)6-4-16/h3-9,11H,10,12-13H2,1-2H3,(H,26,30)(H,27,28,31)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 451.5204 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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