VU6015929
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MedKoo CAT#: 593152

CAS#: unknown

Description: VU6015929 is a selective discoidin domain receptor inhibitor. VU6015929 potently blocks collagen-induced DDR1 activation and collagen-IV production, suggesting DDR1 inhibition as an exciting target for antifibrotic therapy.


Price and Availability

Size Price Shipping out time Quantity
100mg USD 950 2 Weeks
200mg USD 1650 2 Weeks
500mg USD 2650 2 Weeks
1g USD 3650 2 Weeks
2g USD 5950 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-10-26. Prices are subject to change without notice.

VU6015929, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and SDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 593152
Name: VU6015929
CAS#: unknown
Chemical Formula: C24H19F4N5O2
Exact Mass: 485.1475
Molecular Weight: 485.4426
Elemental Analysis: C, 59.38; H, 3.95; F, 15.65; N, 14.43; O, 6.59


Synonym: VU6015929; VU 6015929; VU-6015929

IUPAC/Chemical Name: 4-fluoro-3-(((5-(1-methyl-1H-pyrazol-3-yl)pyridin-3-yl)methyl)amino)-N-(3-(trifluoromethoxy)phenyl)benzamide

InChi Key: IZKVIUJIUTXIRH-UHFFFAOYSA-N

InChi Code: InChI=1S/C24H19F4N5O2/c1-33-8-7-21(32-33)17-9-15(12-29-14-17)13-30-22-10-16(5-6-20(22)25)23(34)31-18-3-2-4-19(11-18)35-24(26,27)28/h2-12,14,30H,13H2,1H3,(H,31,34)

SMILES Code: FC1=CC=C(C(NC2=CC=CC(OC(F)(F)F)=C2)=O)C=C1NCC3=CC(C4=NN(C)C=C4)=CN=C3


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1. Daniel E. Jeffries, Corina M. Borza, Anna L. Blobaum, Ambra Pozzi, and Craig W. Lindsley. Discovery of VU6015929: A Selective Discoidin Domain Receptor 1/2 (DDR1/2) Inhibitor to Explore the Role of DDR1 in Antifibrotic Therapy. ACS Medicinal Chemistry Letters. Article ASAP. DOI: 10.1021/acsmedchemlett.9b00382. (2019).