FAM hydrazide, 5-isomer
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MedKoo CAT#: 558854

CAS#: 2183440-64-2

Description: Many natural and synthetic molecules contain aldehyde or ketone carbonyl groups. These carbonyls react with hydrazides with the formation of hydrazones. The reaction is spontaneous at pH values around neutral, and the resulting hydrazones are very stable. Compounds containing 1,2-diol function, like sugars, can be oxidized with sodium periodate with the formation of carbonyl compounds for the subsequent modification with hydrazides. This is an efficient method for the labeling of glycoproteins (like antibodies), and polysaccharides. FAM hydrazide is a hydrazide label for the attachment of fluorescein, a bright dye for 488 nm channel, to carbonyl compounds


Chemical Structure

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FAM hydrazide, 5-isomer
CAS# 2183440-64-2

Theoretical Analysis

MedKoo Cat#: 558854
Name: FAM hydrazide, 5-isomer
CAS#: 2183440-64-2
Chemical Formula: C21H15ClN2O6
Exact Mass: 426.06
Molecular Weight: 426.810
Elemental Analysis: C, 59.10; H, 3.54; Cl, 8.31; N, 6.56; O, 22.49

Price and Availability

Size Price Availability Quantity
5mg USD 450 2 Weeks
25mg USD 850 2 Weeks
50mg USD 1350 2 Weeks
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Synonym: FAM hydrazide, 5-isomer; BP-23934

IUPAC/Chemical Name: Spiro[isobenzofuran-​1(3H)​,​9'-​[9H]​xanthene]​-​5-​carboxylic acid, 3',​6'-​dihydroxy-​3-​oxo-​, hydrazide, hydrochloride

InChi Key: ZJLTXRWYPNRWBS-UHFFFAOYSA-O

InChi Code: InChI=1S/C21H14N2O6/c22-23-19(26)10-1-4-14-13(7-10)20(27)29-21(14)15-5-2-11(24)8-17(15)28-18-9-12(25)3-6-16(18)21/h1-9,24-25H,22H2,(H,23,26)/p+1

SMILES Code: OC1=CC=C2C(OC(C=C(O)C=C3)=C3C24C5=CC=C(C(N[NH3+])=O)C=C5C(O4)=O)=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 426.81 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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