WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 471034
Description: Nepodin, also know as Musizin; is a naphthol that has been found in Rumex and has diverse biological activities
MedKoo Cat#: 471034
Chemical Formula: C13H12O3
Exact Mass: 216.0786
Molecular Weight: 216.24
Elemental Analysis: C, 72.21; H, 5.59; O, 22.20
Synonym: Nepodin, Musizin; NSC 365795; NSC365795; NSC-365795
IUPAC/Chemical Name: 1-(1,8-dihydroxy-3-methyl-2-naphthalenyl)-ethanone
InChi Key: DMLHPCALHMPJHS-UHFFFAOYSA-N
InChi Code: InChI=1S/C13H12O3/c1-7-6-9-4-3-5-10(15)12(9)13(16)11(7)8(2)14/h3-6,15-16H,1-2H3
SMILES Code: CC(C1=C(C)C=C2C=CC=C(O)C2=C1O)=O
1. Lee, J.H., Kim, Y.G., Khadke, S.K., et al. Inhibition of biofilm formation by Candida albicans and polymicrobial microorganisms by nepodin via hyphal-growth suppression. ACS Infect. Dis. 5(7), 1177-1187 (2019).
2. Grover, J., Kumar, V., Singh, V., et al. Synthesis, biological evaluation, molecular docking and theoretical evaluation of ADMET properties of nepodin and chrysophanol derivatives as potential cyclooxygenase (COX-1, COX-2) inhibitors. Eur. J. Med. Chem. 80, 47-56 (2014)
3. Ha, B.G., Yonezawa, T., Son, M.J., et al. Antidiabetic effect of nepodin, a component of Rumex roots, and its modes of action in vitro and in vivo. Biofactors 40(4), 436-447 (2014).
4. Lee, K.H., and Rhee, K.H. Antimalarial activity of nepodin isolated from Rumex crispus. Arch. Pharm. Res. 36(4), 430-435 (2013)