Nepodin
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 471034

CAS#: 3785-24-8

Description: Nepodin, also know as Musizin; is a naphthol that has been found in Rumex and has diverse biological activities


Price and Availability

Size
Price

5mg
USD 310
Size
Price

10mg
USD 410
Size
Price

Nepodin, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 471034
Name: Nepodin
CAS#: 3785-24-8
Chemical Formula: C13H12O3
Exact Mass: 216.0786
Molecular Weight: 216.24
Elemental Analysis: C, 72.21; H, 5.59; O, 22.20


Synonym: Nepodin, Musizin; NSC 365795; NSC365795; NSC-365795

IUPAC/Chemical Name: 1-(1,8-dihydroxy-3-methyl-2-naphthalenyl)-ethanone

InChi Key: DMLHPCALHMPJHS-UHFFFAOYSA-N

InChi Code: InChI=1S/C13H12O3/c1-7-6-9-4-3-5-10(15)12(9)13(16)11(7)8(2)14/h3-6,15-16H,1-2H3

SMILES Code: CC(C1=C(C)C=C2C=CC=C(O)C2=C1O)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.90.01


References

1. Lee, J.H., Kim, Y.G., Khadke, S.K., et al. Inhibition of biofilm formation by Candida albicans and polymicrobial microorganisms by nepodin via hyphal-growth suppression. ACS Infect. Dis. 5(7), 1177-1187 (2019).

2. Grover, J., Kumar, V., Singh, V., et al. Synthesis, biological evaluation, molecular docking and theoretical evaluation of ADMET properties of nepodin and chrysophanol derivatives as potential cyclooxygenase (COX-1, COX-2) inhibitors. Eur. J. Med. Chem. 80, 47-56 (2014)

3. Ha, B.G., Yonezawa, T., Son, M.J., et al. Antidiabetic effect of nepodin, a component of Rumex roots, and its modes of action in vitro and in vivo. Biofactors 40(4), 436-447 (2014).

4. Lee, K.H., and Rhee, K.H. Antimalarial activity of nepodin isolated from Rumex crispus. Arch. Pharm. Res. 36(4), 430-435 (2013)