WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 585312
CAS#: 54549-02-9
Description: U 43795 is an antitumor agent effective against leukemia L1210.
MedKoo Cat#: 585312
Name: U 43795
CAS#: 54549-02-9
Chemical Formula: C5H7ClN2O4
Exact Mass: 194.0094
Molecular Weight: 194.571
Elemental Analysis: C, 30.87; H, 3.63; Cl, 18.22; N, 14.40; O, 32.89
This product is not in stock, which may be available by custom synthesis.
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Synonym: U 43795; U43795; U-43795; U 43,795 U-43,795; U43,795
IUPAC/Chemical Name: (2S)-2-amino-2-[(4S,5R)-3-chloro-4-hydroxy-4,5-dihydro-1,2-oxazol-5-yl]acetic acid
InChi Key: KUYDILDQEMQBKJ-XZIMBLGRSA-N
InChi Code: InChI=1S/C5H7ClN2O4/c6-4-2(9)3(12-8-4)1(7)5(10)11/h1-3,9H,7H2,(H,10,11)/t1-,2-,3+/m0/s1
SMILES Code: O=C(O)[C@@H](N)[C@@H]1[C@H](O)C(Cl)=NO1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 194.571 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Martin DG, Hanka LJ, Neil GL. A new antitumor agent, (alphas, 4s, 5r)-alpha-amino-3-chloro-4-hydroxy-4,5-dihydro-5-isoxazoleacetic acid (NSC-176324): preliminary evaluation against L 1210 mouse leukemia in vivo. Cancer Chemother Rep. 1974 Nov-Dec;58(6):935-7. PubMed PMID: 4217217.
