U 43795

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 585312

CAS#: 54549-02-9

Description: U 43795 is an antitumor agent effective against leukemia L1210.

Chemical Structure

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U 43795
CAS# 54549-02-9
Instruction

Theoretical Analysis

MedKoo Cat#: 585312
Name: U 43795
CAS#: 54549-02-9
Chemical Formula: C5H7ClN2O4
Exact Mass: 194.01
Molecular Weight: 194.571
Elemental Analysis: C, 30.87; H, 3.63; Cl, 18.22; N, 14.40; O, 32.89

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Synonym: U 43795; U43795; U-43795; U 43,795 U-43,795; U43,795

IUPAC/Chemical Name: (2S)-2-amino-2-[(4S,5R)-3-chloro-4-hydroxy-4,5-dihydro-1,2-oxazol-5-yl]acetic acid

InChi Key: KUYDILDQEMQBKJ-XZIMBLGRSA-N

InChi Code: InChI=1S/C5H7ClN2O4/c6-4-2(9)3(12-8-4)1(7)5(10)11/h1-3,9H,7H2,(H,10,11)/t1-,2-,3+/m0/s1

SMILES Code: O=C(O)[C@@H](N)[C@@H]1[C@H](O)C(Cl)=NO1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 194.57 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Martin DG, Hanka LJ, Neil GL. A new antitumor agent, (alphas, 4s, 5r)-alpha-amino-3-chloro-4-hydroxy-4,5-dihydro-5-isoxazoleacetic acid (NSC-176324): preliminary evaluation against L 1210 mouse leukemia in vivo. Cancer Chemother Rep. 1974 Nov-Dec;58(6):935-7. PubMed PMID: 4217217.