WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 533240
Description: JS-8 is a novel hNPR1 antagonist, inhibiting receptor activity through a noncompetitive mechanism.
MedKoo Cat#: 533240
Chemical Formula: C29H27N3O4
Exact Mass: 481.2002
Molecular Weight: 481.552
Elemental Analysis: C, 72.33; H, 5.65; N, 8.73; O, 13.29
This product is not in stock, which may be available by custom synthesis.
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Synonym: JS-8; JS8; JS 8
IUPAC/Chemical Name: 2-(Benzo[d][1,3]dioxol-5-yl)-1-(3-(2-(benzyloxy)phenyl)-2-methyl-6,7-dihydropyrazolo[1,5-a]pyrimidin-4(5H)-yl)ethan-1-one
InChi Key: UZMOLFNHKVFZND-UHFFFAOYSA-N
InChi Code: InChI=1S/C29H27N3O4/c1-20-28(23-10-5-6-11-24(23)34-18-21-8-3-2-4-9-21)29-31(14-7-15-32(29)30-20)27(33)17-22-12-13-25-26(16-22)36-19-35-25/h2-6,8-13,16H,7,14-15,17-19H2,1H3
SMILES Code: O=C(N1C2=C(C3=CC=CC=C3OCC4=CC=CC=C4)C(C)=NN2CCC1)CC5=CC=C(OCO6)C6=C5
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 481.552 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|