WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 533238
Description: JS-5 is a novel hNPR1 antagonist, inhibiting receptor activity through a noncompetitive mechanism.
MedKoo Cat#: 533238
Chemical Formula: C24H19N3O2
Exact Mass: 381.1477
Molecular Weight: 381.435
Elemental Analysis: C, 75.57; H, 5.02; N, 11.02; O, 8.39
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: JS-5; JS 5; JS5
IUPAC/Chemical Name: 3,5-Dimethyl-4-(6-(2-phenoxyphenyl)imidazo[1,5-a]pyridin-8-yl)isoxazole
InChi Key: ZAPLJRUMVFHDCW-UHFFFAOYSA-N
InChi Code: InChI=1S/C24H19N3O2/c1-16-24(17(2)29-26-16)21-12-18(14-27-15-25-13-22(21)27)20-10-6-7-11-23(20)28-19-8-4-3-5-9-19/h3-15H,1-2H3
SMILES Code: CC1=C(C2=CC(C3=CC=CC=C3OC4=CC=CC=C4)=CN5C2=CN=C5)C(C)=NO1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 381.435 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|