BSJ-04-132

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MedKoo CAT#: 465035

CAS#: 2349356-39-2

Description: BSJ-04-132 shows dose-dependent degradation of CDK4 with maximum degradation at 0.5uM in Jurkat cells.


Price and Availability

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Pricing updated 2020-04-07. Prices are subject to change without notice.

BSJ-04-132 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 465035
Name: BSJ-04-132
CAS#: 2349356-39-2
Chemical Formula: C42H49N11O7
Exact Mass: 819.3816
Molecular Weight: 819.92
Elemental Analysis: C, 61.53; H, 6.02; N, 18.79; O, 13.66


Related CAS #: 2349356-39-2;  

Synonym: BSJ-04-132; BSJ04132; BSJ 04 132;

IUPAC/Chemical Name: 7-cyclopentyl-2-((5-(4-(4-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)piperazin-1-yl)pyridin-2-yl)amino)-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide

InChi Key: GWLSXEHHNOBFOI-UHFFFAOYSA-N

InChi Code: InChI=1S/C42H49N11O7/c1-49(2)40(58)31-22-26-23-45-42(48-37(26)52(31)27-8-3-4-9-27)46-33-14-12-28(24-44-33)51-20-18-50(19-21-51)17-6-5-16-43-35(55)25-60-32-11-7-10-29-36(32)41(59)53(39(29)57)30-13-15-34(54)47-38(30)56/h7,10-12,14,22-24,27,30H,3-6,8-9,13,15-21,25H2,1-2H3,(H,43,55)(H,47,54,56)(H,44,45,46,48)

SMILES Code: CN(C)C(=O)C1=CC2=CN=C(NC3=CC=C(C=N3)N3CCN(CCCCNC(=O)COC4=CC=CC5=C4C(=O)N(C4CCC(=O)NC4=O)C5=O)CC3)N=C2N1C1CCCC1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1. Angew. Chem. Int. Edit., 2019, 58, 6321-6326. (https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201901336)

2. https://graylab.dana-farber.org/probes.html