WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 585295
CAS#: 38150-37-7
Description: U 34599 stimulates the production of tissue-type plasminogen activator.
MedKoo Cat#: 585295
Name: U 34599
CAS#: 38150-37-7
Chemical Formula: C14H16ClN4
Exact Mass: 275.1063
Molecular Weight: 275.76
Elemental Analysis: C, 60.98; H, 5.85; Cl, 12.86; N, 20.32
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: U 34599; U34599; U-34599
IUPAC/Chemical Name: 4H-(1,2,4)Triazolo(4,3-a)(1,4)diazepine, 8-chloro-1,4-dimethyl-6-phenyl-
InChi Key: ZXVWCRRRUKUGPJ-UHFFFAOYSA-N
InChi Code: InChI=1S/C14H16ClN4/c1-17-14-9-18(15)8-13(10-19(14,2)11-16-17)12-6-4-3-5-7-12/h3-9,11H,10H2,1-2H3
SMILES Code: C[N]12C(N(C)N=C2)=CN(Cl)C=C(C3=CC=CC=C3)C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 275.76 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Kooistra T, Toet K, Kluft C, VonVoigtlander PF, Ennis MD, Aiken JW, Boadt JA, Erickson LA. Triazolobenzodiazepines: a new class of stimulators of tissue-type plasminogen activator synthesis in human endothelial cells. Biochem Pharmacol. 1993 Jul 6;46(1):61-7. PubMed PMID: 8347138. 1: Kooistra T, Toet K, Kluft C, VonVoigtlander PF, Ennis MD, Aiken JW, Boadt JA, Erickson LA. Triazolobenzodiazepines: a new class of stimulators of tissue-type plasminogen activator synthesis in human endothelial cells. Biochem Pharmacol. 1993 Jul 6;46(1):61-7. PubMed PMID: 8347138.
