U 34599

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 585295

CAS#: 38150-37-7

Description: U 34599 stimulates the production of tissue-type plasminogen activator.

Chemical Structure

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U 34599
CAS# 38150-37-7
Instruction

Theoretical Analysis

MedKoo Cat#: 585295
Name: U 34599
CAS#: 38150-37-7
Chemical Formula: C14H16ClN4
Exact Mass: 275.11
Molecular Weight: 275.760
Elemental Analysis: C, 60.98; H, 5.85; Cl, 12.86; N, 20.32

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Synonym: U 34599; U34599; U-34599

IUPAC/Chemical Name: 4H-(1,2,4)Triazolo(4,3-a)(1,4)diazepine, 8-chloro-1,4-dimethyl-6-phenyl-

InChi Key: ZXVWCRRRUKUGPJ-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H16ClN4/c1-17-14-9-18(15)8-13(10-19(14,2)11-16-17)12-6-4-3-5-7-12/h3-9,11H,10H2,1-2H3

SMILES Code: C[N]12C(N(C)N=C2)=CN(Cl)C=C(C3=CC=CC=C3)C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 275.76 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Kooistra T, Toet K, Kluft C, VonVoigtlander PF, Ennis MD, Aiken JW, Boadt JA, Erickson LA. Triazolobenzodiazepines: a new class of stimulators of tissue-type plasminogen activator synthesis in human endothelial cells. Biochem Pharmacol. 1993 Jul 6;46(1):61-7. PubMed PMID: 8347138. 1: Kooistra T, Toet K, Kluft C, VonVoigtlander PF, Ennis MD, Aiken JW, Boadt JA, Erickson LA. Triazolobenzodiazepines: a new class of stimulators of tissue-type plasminogen activator synthesis in human endothelial cells. Biochem Pharmacol. 1993 Jul 6;46(1):61-7. PubMed PMID: 8347138.