Iristectorigenin A
new
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 330221

CAS#: 39012-01-6

Description: Iristectorigenin A is an natural isoflavones, showing antioxidant activity.


Price and Availability

Size
Price

500mg
USD 3250
Size
Price

1g
USD 4650
Size
Price

2g
USD 8650

Iristectorigenin A, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 330221
Name: Iristectorigenin A
CAS#: 39012-01-6
Chemical Formula: C17H14O7
Exact Mass: 330.074
Molecular Weight: 330.292
Elemental Analysis: C, 61.82; H, 4.27; O, 33.91


Synonym: Iristectorigenin A

IUPAC/Chemical Name: 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxy-3-methoxyphenyl)-6-methoxy-

InChi Key: CCRPIWFQMLICCY-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H14O7/c1-22-12-5-8(3-4-10(12)18)9-7-24-13-6-11(19)17(23-2)16(21)14(13)15(9)20/h3-7,18-19,21H,1-2H3

SMILES Code: O=C1C(C2=CC=C(O)C(OC)=C2)=COC3=CC(O)=C(OC)C(O)=C13


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.90.01


References

1: Kostić AŽ, Gašić UM, Pešić MB, Stanojević SP, Barać MB, Mačukanović-Jocić MP, Avramov SN, Tešić ŽL. Phytochemical Analysis and Total Antioxidant Capacity of Rhizome, Above-Ground Vegetative Parts and Flower of Three Iris Species. Chem Biodivers. 2019 Mar;16(3):e1800565. doi: 10.1002/cbdv.201800565. Epub 2019 Feb 28. PubMed PMID: 30609204.

2: Li S, Li S, Huang Y, Liu C, Chen L, Zhang Y. Ionic-liquid-based ultrasound-assisted extraction of isoflavones from Belamcanda chinensis and subsequent screening and isolation of potential α-glucosidase inhibitors by ultrafiltration and semipreparative high-performance liquid chromatography. J Sep Sci. 2017 Jun;40(12):2565-2574. doi: 10.1002/jssc.201700258. Epub 2017 Jun 1. PubMed PMID: 28444982.

3: Lim H, Park BK, Shin SY, Kwon YS, Kim HP. Methyl caffeate and some plant constituents inhibit age-related inflammation: effects on senescence-associated secretory phenotype (SASP) formation. Arch Pharm Res. 2017 Apr;40(4):524-535. doi: 10.1007/s12272-017-0909-y. Epub 2017 Mar 15. PubMed PMID: 28299617.

4: Zhang L, Wei K, Xu J, Yang D, Zhang C, Wang Z, Li M. Belamcanda chinensis (L.) DC-An ethnopharmacological, phytochemical and pharmacological review. J Ethnopharmacol. 2016 Jun 20;186:1-13. doi: 10.1016/j.jep.2016.03.046. Epub 2016 Mar 23. Review. PubMed PMID: 27032710.

5: Al-Qudah MA, Saleh AM, Al-Jaber HI, Tashtoush HI, Lahham JN, Abu Zarga MH, Afifi FU, Abu Orabi ST. New isoflavones from Gynandriris sisyrinchium and their antioxidant and cytotoxic activities. Fitoterapia. 2015 Dec;107:15-21. doi: 10.1016/j.fitote.2015.09.020. Epub 2015 Sep 25. PubMed PMID: 26410237.

6: Xie GY, Zhu Y, Shu P, Qin XY, Wu G, Wang Q, Qin MJ. Phenolic metabolite profiles and antioxidants assay of three Iridaceae medicinal plants for traditional Chinese medicine "She-gan" by on-line HPLC-DAD coupled with chemiluminescence (CL) and ESI-Q-TOF-MS/MS. J Pharm Biomed Anal. 2014 Sep;98:40-51. doi: 10.1016/j.jpba.2014.05.008. Epub 2014 May 16. PubMed PMID: 25106824.

7: Zhu Y, Pu BQ, Xie GY, Tian M, Xu FY, Qin MJ. Dynamic changes of flavonoids contents in the different parts of rhizome of Belamcanda chinensis during the thermal drying process. Molecules. 2014 Jul 17;19(7):10440-54. doi: 10.3390/molecules190710440. PubMed PMID: 25036154; PubMed Central PMCID: PMC6271185.

8: Akther N, Andrabi K, Nissar A, Ganaie S, Chandan BK, Gupta AP, Khuswant M, Sultana S, Shawl AS. Hepatoprotective activity of LC-ESI-MS standardized Iris spuria rhizome extract on its main bioactive constituents. Phytomedicine. 2014 Sep 15;21(10):1202-7. doi: 10.1016/j.phymed.2014.04.007. Epub 2014 May 28. PubMed PMID: 24877715.

9: Tarbeeva DV, Fedoreyev SA, Veselova MV, Kalinovskiy AI, Seletskaya LD, Mazurok TI, Bulgakov VP. Polyphenolic compounds from callus cultures of Iris pseudacorus. Nat Prod Commun. 2013 Oct;8(10):1419-20. PubMed PMID: 24354190.

10: Jun HJ, Hoang MH, Lee JW, Yaoyao J, Lee JH, Lee DH, Lee HJ, Seo WD, Hwang BY, Lee SJ. Iristectorigenin B isolated from Belamcanda chinensis is a liver X receptor modulator that increases ABCA1 and ABCG1 expression in macrophage RAW 264.7 cells. Biotechnol Lett. 2012 Dec;34(12):2213-21. doi: 10.1007/s10529-012-1036-y. Epub 2012 Sep 26. PubMed PMID: 23011313.

11: Roger B, Jeannot V, Fernandez X, Cerantola S, Chahboun J. Characterisation and quantification of flavonoids in Iris germanica L. and Iris pallida Lam. resinoids from Morocco. Phytochem Anal. 2012 Sep-Oct;23(5):450-5. doi: 10.1002/pca.1379. Epub 2011 Dec 30. PubMed PMID: 22213588.

12: Zhang YY, Wang Q, Qi LW, Qin XY, Qin MJ. Characterization and determination of the major constituents in Belamcandae Rhizoma by HPLC-DAD-ESI-MS(n). J Pharm Biomed Anal. 2011 Sep 10;56(2):304-14. doi: 10.1016/j.jpba.2011.05.040. Epub 2011 Jun 6. PubMed PMID: 21715119.

13: Lee YS, Kim SH, Kim JK, Lee S, Jung SH, Lim SS. Preparative isolation and purification of seven isoflavones from Belamcanda chinensis. Phytochem Anal. 2011 Sep-Oct;22(5):468-73. doi: 10.1002/pca.1306. Epub 2011 Apr 4. PubMed PMID: 21465599.

14: Huang L, Yang J, Peng Y, Xiao P. [Chemical constituents of Iris dichotoma]. Zhongguo Zhong Yao Za Zhi. 2010 Dec;35(23):3168-71. Chinese. PubMed PMID: 21355241.

15: Qiu QH, Zhang ZG, Wang JH, Lv TS. [Studies on the isoflavonoids of Iris tectorum]. Zhong Yao Cai. 2009 Sep;32(9):1392-4. Chinese. PubMed PMID: 20034214.

16: Kang SW, Kim MC, Kim CY, Jung SH, Um BH. The rapid identification of isoflavonoids from Belamcanda chinensis by LC-NMR and LC-MS. Chem Pharm Bull (Tokyo). 2008 Oct;56(10):1452-4. PubMed PMID: 18827388.

17: Farag SF, Kimura Y, Ito H, Takayasu J, Tokuda H, Hatano T. New isoflavone glycosides from Iris spuria L. (Calizona) cultivated in Egypt. J Nat Med. 2009 Jan;63(1):91-5. doi: 10.1007/s11418-008-0291-7. Epub 2008 Sep 13. PubMed PMID: 18791667.

18: You KM, Jong HG, Kim HP. Inhibition of cyclooxygenase/lipoxygenase from human platelets by polyhydroxylated/methoxylated flavonoids isolated from medicinal plants. Arch Pharm Res. 1999 Feb;22(1):18-24. PubMed PMID: 10071954.