WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 574073
CAS#: 2376990-28-0
Description: VH032 phenol - linker 2 is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development. It incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand.
MedKoo Cat#: 574073
Name: VH032 phenol - linker 2
CAS#: 2376990-28-0
Chemical Formula: C30H47Cl2N5O5S
Exact Mass: 659.2675
Molecular Weight: 660.7
Elemental Analysis: C, 54.54; H, 7.17; Cl, 10.73; N, 10.60; O, 12.11; S, 4.85
Synonym: VH032 phenol - linker 2, VH 032 phenol - linker 2, VH-032 phenol - linker 2
IUPAC/Chemical Name: (2S,4R)-1-((S)-2-Acetamido-3,3-dimethylbutanoyl)-N-(2-((6-aminohexyl)oxy)-4-(4-methylthiazol-5-yl)benzyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride
InChi Key: ZDPHPLMGGQWIRY-SGROTYDGSA-N
InChi Code: InChI=1S/C30H45N5O5S.2ClH/c1-19-26(41-18-33-19)21-10-11-22(25(14-21)40-13-9-7-6-8-12-31)16-32-28(38)24-15-23(37)17-35(24)29(39)27(30(3,4)5)34-20(2)36;;/h10-11,14,18,23-24,27,37H,6-9,12-13,15-17,31H2,1-5H3,(H,32,38)(H,34,36);2*1H/t23-,24+,27-;;/m1../s1
SMILES Code: O=C([C@H]1N(C([C@@H](NC(C)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2OCCCCCCN.[H]Cl.[H]Cl