VH032 phenol - linker 2

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MedKoo CAT#: 574073

CAS#: 2376990-28-0

Description: VH032 phenol - linker 2 is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development. It incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand.

Price and Availability

Size Price Shipping out time Quantity
25mg USD 540 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-07-12. Prices are subject to change without notice.

VH032 phenol - linker 2, purity > 95%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 574073
Name: VH032 phenol - linker 2
CAS#: 2376990-28-0
Chemical Formula: C30H47Cl2N5O5S
Exact Mass: 659.2675
Molecular Weight: 660.7
Elemental Analysis: C, 54.54; H, 7.17; Cl, 10.73; N, 10.60; O, 12.11; S, 4.85

Synonym: VH032 phenol - linker 2, VH 032 phenol - linker 2, VH-032 phenol - linker 2

IUPAC/Chemical Name: (2S,4R)-1-((S)-2-Acetamido-3,3-dimethylbutanoyl)-N-(2-((6-aminohexyl)oxy)-4-(4-methylthiazol-5-yl)benzyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride


InChi Code: InChI=1S/C30H45N5O5S.2ClH/c1-19-26(41-18-33-19)21-10-11-22(25(14-21)40-13-9-7-6-8-12-31)16-32-28(38)24-15-23(37)17-35(24)29(39)27(30(3,4)5)34-20(2)36;;/h10-11,14,18,23-24,27,37H,6-9,12-13,15-17,31H2,1-5H3,(H,32,38)(H,34,36);2*1H/t23-,24+,27-;;/m1../s1

SMILES Code: O=C([C@H]1N(C([C@@H](NC(C)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2OCCCCCCN.[H]Cl.[H]Cl

Technical Data

Solid powder

>95% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: