WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 574052

CAS#: 31721-94-5

Description: 5,7-Dihydroxychromone is a flavone decomposition product with antimicrobial, antioxidant, and neuroprotective properties. It reduces radial growth of the soil pathogenic fungi R. solani and S. rolfsii but has no effect on soil pathogenic bacteria of the genus Bradyrhizobium. 5,7-Dihydroxychromone reduces increases in apoptosis and the levels of reactive oxygen species (ROS) induced by 6-OHDA in SH-SY5Y neuroblastoma cells. It also increases the levels of HO-1, NQO1, and GCLc in SH-SY5Y cells.

Chemical Structure

CAS# 31721-94-5

Theoretical Analysis

MedKoo Cat#: 574052
Name: 5,7-Dihydroxychromone
CAS#: 31721-94-5
Chemical Formula: C9H6O4
Exact Mass: 178.0266
Molecular Weight: 178.14
Elemental Analysis: C, 60.68; H, 3.40; O, 35.92

Price and Availability

Size Price Availability Quantity
1.0mg USD 215.0 2 Weeks
5.0mg USD 390.0 2 Weeks
10.0mg USD 625.0 2 Weeks
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Synonym: 5,7-Dihydroxychromone

IUPAC/Chemical Name: 5,7-dihydroxy-4H-1-benzopyran-4-one


InChi Code: InChI=1S/C9H6O4/c10-5-3-7(12)9-6(11)1-2-13-8(9)4-5/h1-4,10,12H

SMILES Code: OC1=C(C(C=CO2)=O)C2=CC(O)=C1

Appearance: A crystalline solid

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 178.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Vaughn, S.F. Phytotoxic and antimicrobial activity of 5,7-dihydroxychromone from peanut shells. J. Chem. Ecol. 21(2), 107-115 (1995).

2. Kim, D.-W., Lee, K.-t., Kwon, J., et al. Neuroprotection against 6-OHDA-induced oxidative stress and apoptosis in SH-SY5Y cells by 5,7-Dihydroxychromone: Activation of the Nrf2/ARE pathway. Life Sci. 130, 25-30 (2015).