SYN-2903

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 585231

CAS#: 210563-03-4

Description: SYN-2903 is a derivative of the triazole antifungal agent SYN-2869.


Chemical Structure

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SYN-2903
CAS# 210563-03-4

Theoretical Analysis

MedKoo Cat#: 585231
Name: SYN-2903
CAS#: 210563-03-4
Chemical Formula: C32H30F6N8O2
Exact Mass: 672.2396
Molecular Weight: 672.6364
Elemental Analysis: C, 57.14; H, 4.50; F, 16.95; N, 16.66; O, 4.76

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: SYN-2903; SYN2903; SYN 2903

IUPAC/Chemical Name: 3H-1,2,4-Triazol-3-one, 4-(4-(4-((1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl)-1-piperazinyl)-3-fluorophenyl)-2,4-dihydro-2-((4-(trifluoromethyl)phenyl)methyl)-

InChi Key: PCYZZKYRNGSDMF-ROTAYESASA-N

InChi Code: InChI=1S/C32H30F6N8O2/c1-21(31(48,17-44-19-39-18-40-44)26-8-6-24(33)14-27(26)34)42-10-12-43(13-11-42)29-9-7-25(15-28(29)35)45-20-41-46(30(45)47)16-22-2-4-23(5-3-22)32(36,37)38/h2-9,14-15,18-21,48H,10-13,16-17H2,1H3/t21-,31-/m1/s1

SMILES Code: O=C1N(CC2=CC=C(C(F)(F)F)C=C2)N=CN1C3=CC=C(N4CCN([C@H](C)[C@@](O)(C5=CC=C(F)C=C5F)CN6N=CN=C6)CC4)C(F)=C3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 672.6364 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Khan JK, Montaseri H, Poglod M, Bu HZ, Zuo Z, Salama SM, Daneshtalab M, Micetich RG. Interspecies comparison of pharmacokinetics of the novel triazole antifungal agent SYN-2869 and its derivatives. Antimicrob Agents Chemother. 2000 Apr;44(4):910-5. PubMed PMID: 10722490; PubMed Central PMCID: PMC89791.

2: Bu HZ, Khan JK, Poglod M, Micetich RG. Liquid chromatographic-electrospray tandem mass spectrometric determination of novel antifungal agents in plasma. J Chromatogr B Biomed Sci Appl. 1999 Mar 19;724(2):311-7. PubMed PMID: 10219673.