WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 533077
CAS#: N/A
Description: J014 is a Novel cGAS-specific inhibitor for repression of dsDNA-triggered interferon expression ( IC50 of 100 nM and 60.0 nM for h-cGAS and m-cGAS, respectively).
MedKoo Cat#: 533077
Name: J014
CAS#: N/A
Chemical Formula: C15H11N5O3
Exact Mass: 309.0862
Molecular Weight: 309.285
Elemental Analysis: C, 58.25; H, 3.59; N, 22.64; O, 15.52
J014 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.
Synonym: J014; J-014; J 014
IUPAC/Chemical Name: 4-Nitro-N-(4-phenylpyridin-2-yl)-1H-pyrazole-5-carboxamide
InChi Key: OTSHTQSPIKHBMM-UHFFFAOYSA-N
InChi Code: InChI=1S/C15H11N5O3/c21-15(14-12(20(22)23)9-17-19-14)18-13-8-11(6-7-16-13)10-4-2-1-3-5-10/h1-9H,(H,17,19)(H,16,18,21)
SMILES Code: O=C(C1=C([N+]([O-])=O)C=NN1)NC2=NC=CC(C3=CC=CC=C3)=C2
The following data is based on the product molecular weight 309.285 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |