(±)-α-Tocopherol acetate
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MedKoo CAT#: 574016

CAS#: 7695-91-2

Description: (±)-α-Tocopherol acetate is the acetate form of (±)-α-tocopherol, a biologically active form of vitamin E. It prevents reductions in the percentage of embryos developing into blastocysts, levels of glutathione (GSH), and prevents increases in oxidative stress. (±)-α-Tocopherol acetate has been shown to prevent body weight loss and decreases in pulmonary dynamic compliance in mice exposed to sidestream cigarette smoke but not in sham exposure animals. However, it also increases the levels of IL-1β, IL-4, and IFN-γ in the bronchoalveolar lavage fluid (BALF) of sidestream cigarette-exposed, but not sham exposure, mice.

Chemical Structure

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(±)-α-Tocopherol acetate
CAS# 7695-91-2
Instruction

Theoretical Analysis

MedKoo Cat#: 574016
Name: (±)-α-Tocopherol acetate
CAS#: 7695-91-2
Chemical Formula: C31H52O3
Exact Mass: 472.39
Molecular Weight: 472.750
Elemental Analysis: C, 78.76; H, 11.09; O, 10.15

Price and Availability

Size Price Availability Quantity
25g USD 205
50g USD 335
100g USD 520
250g USD 950
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Synonym: (±)-α-Tocopherol acetate, all-rac-α-Tocopherol Acetate, DL-α-Tocopherol Acetate, DL-Vitamin E acetate

IUPAC/Chemical Name: 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol, 6-acetate

InChi Key: ZAKOWWREFLAJOT-UHFFFAOYSA-N

InChi Code: InChI=1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3

SMILES Code: CC1=C2C(CCC(CCCC(C)CCCC(C)CCCC(C)C)(C)O2)=C(C)C(OC(C)=O)=C1C

Appearance: A liquid

Purity: >95% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 472.75 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Sakamoto, N., Ozawa, M., Yokotani-Tomita, K., et al. DL-α-Tocopherol acetate mitigates maternal hyperthermia-induced pre-implantation embryonic death accompanied by a reduction of physiological oxidative stress in mice. Reproduction 135(4), 489-496 (2008).

2. Wang, S., Sun, N.N., Zhang, J., et al. Immunomodulatory effects of high-dose α-tocopherol acetate on mice subjected to sidestream cigarette smoke. Toxicology 175(1-3), 235-245 (2002).