Bz-IEGR-pNA acetate
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 574003

CAS#: 1325307-57-0

Description: Bz-IEGR-pNA acetate is a colorimetric substrate for Factor Xa. Factor Xa preferentially binds to and cleaves the Ile-Glu-Gly-Arg (IEGR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of Factor Xa activity.


Price and Availability

Size
Price

1mg
USD 205
25mg
USD 1150
Size
Price

5mg
USD 405
Size
Price

10mg
USD 650

Bz-IEGR-pNA acetate, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 574003
Name: Bz-IEGR-pNA acetate
CAS#: 1325307-57-0
Chemical Formula: C34H47N9O11
Exact Mass: 757.3395
Molecular Weight: 757.8
Elemental Analysis: C, 53.89; H, 6.25; N, 16.64; O, 23.22


Synonym: Bz-IEGR-pNA acetate, Bz-Ile-Glu-Gly-Arg-pNA, Bz-Ile-Glu-Gly-Arg-p-nitroanilide, Factor Xa Chromogenic Substrate

IUPAC/Chemical Name: N-benzoyl-L-isoleucyl-L-α-glutamylglycyl-N-(4-nitrophenyl)-L-argininamide, monoacetate

InChi Key: ITXQNZUGLZNGBM-PJSBSAQXSA-N

InChi Code: InChI=1S/C32H43N9O9.C2H4O2/c1-3-19(2)27(40-28(45)20-8-5-4-6-9-20)31(48)39-24(15-16-26(43)44)29(46)36-18-25(42)38-23(10-7-17-35-32(33)34)30(47)37-21-11-13-22(14-12-21)41(49)50;1-2(3)4/h4-6,8-9,11-14,19,23-24,27H,3,7,10,15-18H2,1-2H3,(H,36,46)(H,37,47)(H,38,42)(H,39,48)(H,40,45)(H,43,44)(H4,33,34,35);1H3,(H,3,4)/t19-,23-,24-,27-;/m0./s1

SMILES Code: O=C([C@H](CCCNC(N)=N)NC(CNC([C@@H](NC([C@](NC(C1=CC=CC=C1)=O)([H])[C@@H](C)CC)=O)CCC(O)=O)=O)=O)NC2=CC=C([N+]([O-])=O)C=C2.CC(O)=O


Technical Data

Appearance:
A crystalline solid

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.90.01


Additional Information

λmax: 224, 314 nm


References

1. Aruell, L., Friberger, P., Karlsson, G., et al. A new sensitive and highly specific chromogenic peptide substrate for factor Xa. Thromb. Res. 11(5), 595-609 (1977).