ZAP-180013
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MedKoo CAT#: 585162

CAS#: 873080-25-2

Description: ZAP-180013 inhibits interaction with ITAMs (immunoreceptor tyrosine-based activation motifs).


Price and Availability

Size Price Shipping out time Quantity
10mg USD 285 2 Weeks
50mg USD 895 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-10-30. Prices are subject to change without notice.

ZAP-180013, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 585162
Name: ZAP-180013
CAS#: 873080-25-2
Chemical Formula: C19H17Cl2N3O4S
Exact Mass: 453.0317
Molecular Weight: 454.322
Elemental Analysis: C, 50.23; H, 3.77; Cl, 15.61; N, 9.25; O, 14.09; S, 7.06


Synonym: ZAP 180013; ZAP180013; ZAP-180013

IUPAC/Chemical Name: 5-Chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)-4-pyrimidinecarboxamide

InChi Key: GTWKIPDKVRLUKN-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H17Cl2N3O4S/c1-2-29(26,27)19-22-10-16(21)17(23-19)18(25)24(12-15-4-3-9-28-15)11-13-5-7-14(20)8-6-13/h3-10H,2,11-12H2,1H3

SMILES Code: O=C(C1=NC(S(=O)(CC)=O)=NC=C1Cl)N(CC2=CC=C(Cl)C=C2)CC3=CC=CO3


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Certificate of Analysis:

Safety Data Sheet (SDS):

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

Visperas et al (2017) Identification of inhibitors of the association of ZAP-70 with the T-cell receptor by high-throughput screen. SLAS.Discov. 22 324 PMID: 27932698