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MedKoo CAT#: 555645

CAS#: 2101626-26-8

Description: GSK2894631A is a hematopoietic PGD synthase (HPGDS) inhibitor.

Price and Availability

Size Price Shipping out time Quantity
100mg USD 750 2 Weeks
200mg USD 1250 2 Weeks
500mg USD 2450 2 Weeks
1g USD 3450 2 Weeks
2g USD 5850 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-05-29. Prices are subject to change without notice.

GSK2894631A, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 555645
Name: GSK2894631A
CAS#: 2101626-26-8
Chemical Formula: C20H24F2N2O3
Exact Mass: 378.1755
Molecular Weight: 378.4198
Elemental Analysis: C, 63.48; H, 6.39; F, 10.04; N, 7.40; O, 12.68

Synonym: GSK2894631A; GSK-2894631A; GSK 2894631A; GSK2894631; GSK-2894631; GSK 2894631;

IUPAC/Chemical Name: 7-(Difluoromethoxy)-N-[trans-4-(1-hydroxy-1-methylethyl)cyclohexyl]-3-quinolinecarboxamide


InChi Code: InChI=1S/C20H24F2N2O3/c1-20(2,26)14-4-6-15(7-5-14)24-18(25)13-9-12-3-8-16(27-19(21)22)10-17(12)23-11-13/h3,8-11,14-15,19,26H,4-7H2,1-2H3,(H,24,25)/t14-,15-

SMILES Code: O=C(C1=CC2=CC=C(OC(F)F)C=C2N=C1)N[C@H]3CC[C@H](C(C)(O)C)CC3

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:

Additional Information

Injured tendons heal through the formation of a fibrovascular scar that has inferior mechanical properties compared to native tendon tissue. Reducing inflammation that occurs as a result of the injury could limit scar formation and improve functional recovery of tendons. Prostaglandin D2 (PGD2 ) plays an important role in promoting inflammation in some injury responses and chronic disease processes, and the inhibition of PGD2 has improved healing and reduced disease burden in animal models and early clinical trials. Based on these findings, we sought to determine the role of PGD2 signaling in the healing of injured tendon tissue.


Sarver DC, Sugg KB, Talarek JR, et al. Prostaglandin D2 signaling is not involved in the recovery of rat hind limb tendons from injury. Physiol Rep. 2019;7(22):e14289. doi:10.14814/phy2.14289