WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 532720
Description: E09241 is a novel OPG/RANKL upregulator, increasing OPG expression without affecting RANKL expression, promoting osteoblast differentiation while inhibiting osteoclast differentiation, regulating OPG expression through canonical Wnt/β-catenin signaling.
MedKoo Cat#: 532720
Chemical Formula: C11H9ClN2O2
Exact Mass: 236.0353
Molecular Weight: 236.655
Elemental Analysis: C, 55.83; H, 3.83; Cl, 14.98; N, 11.84; O, 13.52
This product is not in stock, which may be available by custom synthesis.
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Synonym: E09241; E-09241; E 09241;
IUPAC/Chemical Name: 5-Chloro-N-(4-methylpyridin-2-yl)furan-2-carboxamide
InChi Key: XUZSJAATNRKRPD-UHFFFAOYSA-N
InChi Code: InChI=1S/C11H9ClN2O2/c1-7-4-5-13-10(6-7)14-11(15)8-2-3-9(12)16-8/h2-6H,1H3,(H,13,14,15)
SMILES Code: O=C(C1=CC=C(Cl)O1)NC2=NC=CC(C)=C2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 236.655 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Han X, Gong S, Li N, Wang X, Liu P, Xu Y, He X, Jiang W, Si S. A Novel Small
Molecule Which Increases Osteoprotegerin Expression and Protects Against
Ovariectomy-Related Bone Loss in Rats. Front Pharmacol. 2019 Mar 11;10:103. doi:
10.3389/fphar.2019.00103. eCollection 2019. PubMed PMID: 30914947; PubMed Central