Damilen maleate

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MedKoo CAT#: 573859

CAS#: 30227-34-0

Description: Damilen maleate is the maleate salt of Amitriptyline --- a tricyclic antidepressant with anticholinergic and sedative properties.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-07-10. Prices are subject to change without notice.

Damilen maleate is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 573859
Name: Damilen maleate
CAS#: 30227-34-0
Chemical Formula: C24H27NO4
Exact Mass: 393.194
Molecular Weight: 393.48
Elemental Analysis: C, 73.26; H, 6.92; N, 3.56; O, 16.26


Synonym: Amitriptyline maleate, Damilen maleate

IUPAC/Chemical Name: 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine maleate

InChi Key: DBDNMOMAYUONLS-BTJKTKAUSA-N

InChi Code: 1S/C20H23N.C4H4O4/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;5-3(6)1-2-4(7)8/h3-6,8-12H,7,13-15H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

SMILES Code: CN(C)CCC=C1c2ccccc2CCc3ccccc13.OC(=O)\C=C/C(=O)O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Han FY, Kuo A, Nicholson JR, Corradinni L, Smith MT. Comparative Analgesic Efficacy of Pregabalin Administered According to Either a Prevention Protocol or an Intervention Protocol in Rats with Cisplatin-induced Peripheral Neuropathy. Clin Exp Pharmacol Physiol. 2018 May 21. doi: 10.1111/1440-1681.12971. [Epub ahead of print] PubMed PMID: 29781509.

2: Øiestad ÅML, Karinen R, Rogde S, Nilsen S, Boye Eldor KB, Brochmann GW, Arnestad M, Øiestad EL, Peres MD, Kristoffersen L, Vindenes V. Comparative Study of Postmortem Concentrations of Antidepressants in Several Different Matrices. J Anal Toxicol. 2018 May 14. doi: 10.1093/jat/bky030. [Epub ahead of print] PubMed PMID: 29762694.

3: Everitt H, Baldwin DS, Stuart B, Lipinska G, Mayers A, Malizia AL, Manson CC, Wilson S. Antidepressants for insomnia in adults. Cochrane Database Syst Rev. 2018 May 14;5:CD010753. doi: 10.1002/14651858.CD010753.pub2. [Epub ahead of print] Review. PubMed PMID: 29761479.