R 151885

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 585079

CAS#: 76674-14-1

Description: R 151885 delays ovulation in rats.

Chemical Structure

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R 151885
CAS# 76674-14-1
Instruction

Theoretical Analysis

MedKoo Cat#: 585079
Name: R 151885
CAS#: 76674-14-1
Chemical Formula: C16H13F2N3O
Exact Mass: 301.10
Molecular Weight: 301.297
Elemental Analysis: C, 63.78; H, 4.35; F, 12.61; N, 13.95; O, 5.31

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: R 151885; R151885; R-151885

IUPAC/Chemical Name: 1H-1,2,4-Triazole-1-ethanol, alpha,alpha-bis(4-fluorophenyl)-

InChi Key: OGZYWIZILQBEJI-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H13F2N3O/c17-14-5-1-12(2-6-14)16(22,9-21-11-19-10-20-21)13-3-7-15(18)8-4-13/h1-8,10-11,22H,9H2

SMILES Code: OC(C1=CC=C(F)C=C1)(C2=CC=C(F)C=C2)CN3N=CN=C3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 301.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Milne CM, Hasmall RL, Russell A, Watson SC, Vaughan Z, Middleton MC. Reduced estradiol production by a substituted triazole results in delayed ovulation in rats. Toxicol Appl Pharmacol. 1987 Sep 30;90(3):427-35. PubMed PMID: 3310336.

2: Wickings EJ, Middleton MC, Hillier SG. Non-steroidal inhibition of granulosa cell aromatase activity in vitro. J Steroid Biochem. 1987 Jun;26(6):641-6. PubMed PMID: 3112466.

3: Middleton MC, Milne CM, Moreland S, Hasmall RL. Ovulation in rats is delayed by a substituted triazole. Toxicol Appl Pharmacol. 1986 Apr;83(2):230-9. PubMed PMID: 3083533.