p32-IN-M36

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 558670

CAS#: 802555-85-7

Description: p32-IN-M36 is an inhibitor of p32 mitochondrial protein, which binds directly to p32 and blocks p32 association with LyP-1.


Price and Availability

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p32-IN-M36 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 558670
Name: p32-IN-M36
CAS#: 802555-85-7
Chemical Formula: C23H28N8O2
Exact Mass: 448.2335
Molecular Weight: 448.53
Elemental Analysis: C, 61.59; H, 6.29; N, 24.98; O, 7.13


Synonym: p32 IN-M36; p32-IN M36; p32-IN-M36; p32 inhibitor M36

IUPAC/Chemical Name: 1,1'-(Propane-1,3-diyl)bis(3-(3-(4,5-dihydro-1H-imidazol-2-yl)phenyl)urea)

InChi Key: HHFOXYBNULCICF-UHFFFAOYSA-N

InChi Code: InChI=1S/C23H28N8O2/c32-22(30-18-6-1-4-16(14-18)20-24-10-11-25-20)28-8-3-9-29-23(33)31-19-7-2-5-17(15-19)21-26-12-13-27-21/h1-2,4-7,14-15H,3,8-13H2,(H,24,25)(H,26,27)(H2,28,30,32)(H2,29,31,33)

SMILES Code: O=C(NC1=CC=CC(C2=NCCN2)=C1)NCCCNC(NC3=CC=CC(C4=NCCN4)=C3)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.90.01


References

1: Yenugonda V, Nomura N, Kouznetsova V, Tsigelny I, Fogal V, Nurmemmedov E, Kesari S, Babic I. A novel small molecule inhibitor of p32 mitochondrial protein overexpressed in glioma. J Transl Med. 2017 Oct 18;15(1):210. doi: 10.1186/s12967-017-1312-7. PubMed PMID: 29047383; PubMed Central PMCID: PMC5648515.