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MedKoo CAT#: 565778

CAS#: 874590-32-6

Description: M1001 is a novel allosteric agonist of hypoxia-inducible factor-2α subunit (hif-2α), significantly displacing pocket residue y281

Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-08-11. Prices are subject to change without notice.

M1001 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 565778
Name: M1001
CAS#: 874590-32-6
Chemical Formula: C17H17N3O2S
Exact Mass: 327.1041
Molecular Weight: 327.402
Elemental Analysis: C, 62.37; H, 5.23; N, 12.83; O, 9.77; S, 9.79

Synonym: M1001; M 1001; M-1001

IUPAC/Chemical Name: 3-((2-(Pyrrolidin-1-yl)phenyl)amino)benzo[d]isothiazole 1,1-dioxide


InChi Code: InChI=1S/C17H17N3O2S/c21-23(22)16-10-4-1-7-13(16)17(19-23)18-14-8-2-3-9-15(14)20-11-5-6-12-20/h1-4,7-10H,5-6,11-12H2,(H,18,19)


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: den Bakker HC, Manuel CS, Fortes ED, Wiedmann M, Nightingale KK. Genome sequencing identifies Listeria fleischmannii subsp. coloradonensis subsp. nov., isolated from a ranch. Int J Syst Evol Microbiol. 2013 Sep;63(Pt 9):3257-68. doi: 10.1099/ijs.0.048587-0. Epub 2013 Mar 22. PubMed PMID: 23524352.

2: Wang SL, Shieh ST, Pai CS. Production, purification and characterization of two proteinaceous hen-egg-white lysozyme inhibitors from Pseudomonas aeruginosa M-1001. Proc Natl Sci Counc Repub China B. 1995 Jul;19(3):166-75. PubMed PMID: 7480363.

3: Hukami K. [An attempt at training color vision defectives with Sanvista (M-1001)]. Nippon Ganka Gakkai Zasshi. 1966 Jun;70(6):589-92. Japanese. PubMed PMID: 5297148.

4: Perloff D, Sokolow M, Cowan R. Clinical relevance of ambulatory blood pressure measurements. Biotelem Patient Monit. 1981;8(1-2):67-80. PubMed PMID: 7295924.

5: Wang SL, Pai CS, Shieh ST. Production of lytic enzyme from Pseudomonas aeruginosa M-1001. Proc Natl Sci Counc Repub China B. 1995 Oct;19(4):216-24. PubMed PMID: 8742619.