WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 565689
Description: IA-alkyne is a novel thiol-reactive and clickable proble for protein-protein interaction studies
MedKoo Cat#: 565689
Chemical Formula: C8H12INO
Exact Mass: 264.9964
Molecular Weight: 265.0945
Elemental Analysis: C, 36.25; H, 4.56; I, 47.87; N, 5.28; O, 6.04
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: IA-alkyne; IA alkyne; IAalkyne
IUPAC/Chemical Name: N-(5-Hexyn-1-yl)-2-iodoacetamide
InChi Key: YCRUVTMZPHEOAM-UHFFFAOYSA-N
InChi Code: InChI=1S/C8H12INO/c1-2-3-4-5-6-10-8(11)7-9/h1H,3-7H2,(H,10,11)
SMILES Code: O=C(NCCCCC#C)CI
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 265.0945 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Abo M, Li C, Weerapana E. Isotopically-Labeled Iodoacetamide-Alkyne Probes for Quantitative Cysteine-Reactivity Profiling. Mol Pharm. 2018 Mar 5;15(3):743-749. doi: 10.1021/acs.molpharmaceut.7b00832. Epub 2017 Dec 6. PubMed PMID: 29172527; PubMed Central PMCID: PMC5841085.