BAY-293 HCl

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MedKoo CAT#: 565626

CAS#: Unknown (HCl)

Description: BAY-293 is a novel potent sos1 inhibitor, blocking ras activation via disruption of the ras-sos1 interaction

Price and Availability

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Pricing updated 2020-07-11. Prices are subject to change without notice.

BAY-293 HCl is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 565626
Name: BAY-293 HCl
CAS#: Unknown (HCl)
Chemical Formula: C25H30Cl2N4O2S
Exact Mass: 448.1933
Molecular Weight: 521.501
Elemental Analysis: C, 57.58; H, 5.80; Cl, 13.60; N, 10.74; O, 6.14; S, 6.15

Related CAS #: 2244904-70-7   2244904-69-4 (S-isomer)   2244904-14 (racemic)    

Synonym: BAY-293; BAY 293; BAY293; BAY-293 HCl; BAY-293 hydrochloride; BAY-293 dihydrochloride

IUPAC/Chemical Name: (R)-6,7-Dimethoxy-2-methyl-N-(1-(4-(2-((methylamino)methyl)phenyl)thiophen-2-yl)ethyl)quinazolin-4-amine dihydrochloride


InChi Code: InChI=1S/C25H28N4O2S.2ClH/c1-15(24-10-18(14-32-24)19-9-7-6-8-17(19)13-26-3)27-25-20-11-22(30-4)23(31-5)12-21(20)28-16(2)29-25;;/h6-12,14-15,26H,13H2,1-5H3,(H,27,28,29);2*1H/t15-;;/m1../s1

SMILES Code: C[C@@H](NC1=C2C=C(OC)C(OC)=CC2=NC(C)=N1)C3=CC(C4=CC=CC=C4CNC)=CS3.[H]Cl.[H]Cl

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Hillig RC, Sautier B, Schroeder J, Moosmayer D, Hilpmann A, Stegmann CM, Werbeck ND, Briem H, Boemer U, Weiske J, Badock V, Mastouri J, Petersen K, Siemeister G, Kahmann JD, Wegener D, Böhnke N, Eis K, Graham K, Wortmann L, von Nussbaum F, Bader B. Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction. Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2551-2560. doi: 10.1073/pnas.1812963116. Epub 2019 Jan 25. PubMed PMID: 30683722; PubMed Central PMCID: PMC6377443.