AM-92016 HCl
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555585

CAS#: 133229-11-5 (HCl)

Description: AM-92016 is an oxypropanolamine analogue of sotalol, has been shown to possess Class III anti-arrhythmic properties in-vitro at concentrations showing 1000 times more potency than sotalol. AM 92016 exhibited proarrhythmic rather than antiarrhythmic activity when administered in-vivo to either guinea-pigs or pigs.


Price and Availability

Size
Price

25mg
USD 250
200mg
USD 1250
2g
USD 5850
Size
Price

50mg
USD 450
500mg
USD 1950
Size
Price

100mg
USD 750
1g
USD 3250

AM-92016 HCl, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 555585
Name: AM-92016 HCl
CAS#: 133229-11-5 (HCl)
Chemical Formula: C19H25Cl3N2O4S
Exact Mass:
Molecular Weight: 483.829
Elemental Analysis: C, 47.17; H, 5.21; Cl, 21.98; N, 5.79; O, 13.23; S, 6.63


Related CAS #: 133229-23-9 (free base)   133229-11-5 (HCl)    

Synonym: AM-92016 HCl; AM 92016 HCl; AM92016 HCl; AM-92016 hydrochloride

IUPAC/Chemical Name: N-(4-(3-((3,4-dichlorophenethyl)(methyl)amino)-2-hydroxypropoxy)phenyl)methanesulfonamide hydrochloride

InChi Key: TXOARFPCQOBODS-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H24Cl2N2O4S.ClH/c1-23(10-9-14-3-8-18(20)19(21)11-14)12-16(24)13-27-17-6-4-15(5-7-17)22-28(2,25)26;/h3-8,11,16,22,24H,9-10,12-13H2,1-2H3;1H

SMILES Code: OC(CN(C)CCC1=CC=C(Cl)C(Cl)=C1)COC2=CC=C(NS(=O)(C)=O)C=C2.[H]Cl


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.90.01


References

1: Katsuki H, Shinohara A, Fujimoto S, Kume T, Akaike A. Tetraethylammonium
exacerbates ischemic neuronal injury in rat cerebrocortical slice cultures. Eur J
Pharmacol. 2005 Jan 31;508(1-3):85-91. Epub 2005 Jan 6. PubMed PMID: 15680257.

2: Hagerty MJ, Wainwright CL, Kane KA. The in-vivo cardiovascular effects of a
putative class III anti-arrhythmic drug, AM 92016. J Pharm Pharmacol. 1996
Apr;48(4):417-21. PubMed PMID: 8794994.