MDK-7553 HCl

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MedKoo CAT#: 565597

CAS#: MDK-7553 HCl

Description: MDK-7553, also known as CD38 inhibitor 78c and Compound-78c, is a potent CD38 inhibitor. MDK-7553 has CAS#1700637-55-3, which was reported in J Med Chem. 2015 Apr 23;58(8):3548-71. For the convenience of scientific communication, we name it as MDK-7553. The last four digits of CAS# were used for its name.

Chemical Structure

MDK-7553 HCl
CAS# MDK-7553 HCl

Theoretical Analysis

MedKoo Cat#: 565597
Name: MDK-7553 HCl
CAS#: MDK-7553 HCl
Chemical Formula: C22H28ClN3O3S
Exact Mass: 413.1773
Molecular Weight: 449.99
Elemental Analysis: C, 58.72; H, 6.27; Cl, 7.88; N, 9.34; O, 10.67; S, 7.12

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 1700637-55-3 (free base)   MDK-7553 HCl    

Synonym: CD38 inhibitor 78c; Compound-78c; CD38i_78c; 78c; Cluster of Differentiation 38 Inhibitor; MDK-7553; MDK 7553; MDK7553; CD38-IN-78c; CD38 IN-78c; CD38IN-78c: CD38 inhibitor 78c;

IUPAC/Chemical Name: 4-(((1r,4r)-4-(2-Methoxyethoxy)cyclohexyl)amino)-1-methyl-6-(thiazol-5-yl)quinolin-2(1H)-one hydrochloride


InChi Code: InChI=1S/C22H27N3O3S.ClH/c1-25-20-8-3-15(21-13-23-14-29-21)11-18(20)19(12-22(25)26)24-16-4-6-17(7-5-16)28-10-9-27-2;/h3,8,11-14,16-17,24H,4-7,9-10H2,1-2H3;1H/t16-,17-;

SMILES Code: O=C1N(C)C2=C(C=C(C3=CN=CS3)C=C2)C(N[C@H]4CC[C@H](OCCOC)CC4)=C1.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 449.99 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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