Benfotiamine sodium

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MedKoo CAT#: 565590

CAS#: 22457-89-2

Description: Benfotiamine (rINN, or S-benzoylthiamine O-monophosphate) is a synthetic S-acyl derivative of thiamine (vitamin B1) that is marketed as a pharmaceutical drug in most countries, and as a thiamine derivative supplement for treating diabetic neuropathy.

Price and Availability

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Pricing updated 2020-08-15. Prices are subject to change without notice.

Benfotiamine sodium is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 565590
Name: Benfotiamine sodium
CAS#: 22457-89-2
Chemical Formula: C19H21N4Na2O6PS
Exact Mass: 466.1076
Molecular Weight: 510.4123
Elemental Analysis: C, 44.71; H, 4.15; N, 10.98; Na, 9.01; O, 18.81; P, 6.07; S, 6.28

Related CAS #: 147317-17-7 (semihydrate)   22457-89-2 (free acid)    

Synonym: Benfotiamine; Benfotiamine sodium; BRN-0771326; BTMP; CB-8088; CB8088; CB 8088; Berdi; Betivina; Biotamin; Benfotiamine; S-benzoylthiamine O-monophosphate.

IUPAC/Chemical Name: sodium (Z)-4-(N-((4-amino-2-methylpyrimidin-5-yl)methyl)formamido)-3-((phenylcarbonothioyl)oxy)pent-3-en-1-yl phosphate


InChi Code: InChI=1S/C19H23N4O6PS.2Na/c1-13(23(12-24)11-16-10-21-14(2)22-18(16)20)17(8-9-28-30(25,26)27)29-19(31)15-6-4-3-5-7-15;;/h3-7,10,12H,8-9,11H2,1-2H3,(H2,20,21,22)(H2,25,26,27);;/q;2*+1/p-2/b17-13-;;

SMILES Code: S=C(O/C(CCOP(O[Na])(O[Na])=O)=C(C)\N(C=O)CC1=CN=C(N=C1N)C)C2=CC=CC=C2

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


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