WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 565558
Description: P4Q-391 is an antimalarial agent.
MedKoo Cat#: 565558
Chemical Formula: C24H16ClF4NO4
Exact Mass: 493.0704
Molecular Weight: 493.84
Elemental Analysis: C, 58.37; H, 3.27; Cl, 7.18; F, 15.39; N, 2.84; O, 12.96
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: P4Q-391; P4Q 391; P4Q391;
IUPAC/Chemical Name: 6-Chloro-3-[2-fluoro-4-[4-(trifluoromethoxy)phenoxy]phenyl]-7-methoxy-2-methyl-4(1H)-quinolinone
InChi Key: NNNAUTBFAMPSKL-UHFFFAOYSA-N
InChi Code: InChI=1S/C24H16ClF4NO4/c1-12-22(23(31)17-10-18(25)21(32-2)11-20(17)30-12)16-8-7-15(9-19(16)26)33-13-3-5-14(6-4-13)34-24(27,28)29/h3-11H,1-2H3,(H,30,31)
SMILES Code: O=C1C(C2=C(F)C=C(C=C2)OC3=CC=C(C=C3)OC(F)(F)F)=C(NC4=C1C=C(C(OC)=C4)Cl)C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 493.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
Brockmeyer F, Manetsch R. Progress in the Optimization of 4(1H)-Quinolone Derivatives as Antimalarials Targeting the Erythrocytic, the Exoerythrocytic and the Transmitting Stages of the Malaria Parasite. Chimia (Aarau). 2017 Apr 26;71(4):213-219. doi: 10.2533/chimia.2017.213. PMID: 28446339.