YUN90389

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 565496

CAS#: 1673590-38-9

Description: YUN90389, also known as PPARalpha/delta-IN-11, is a the first reported pparα/δ dual antagonist. YUN90389 was first reported in Bioorganic & Medicinal Chemistry Letters (2019), 29(3), 503-508. YUN90389 has CAS#1673590-38-9. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).


Chemical Structure

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YUN90389
CAS# 1673590-38-9

Theoretical Analysis

MedKoo Cat#: 565496
Name: YUN90389
CAS#: 1673590-38-9
Chemical Formula: C34H29F4N3O4
Exact Mass: 619.2094
Molecular Weight: 619.6166
Elemental Analysis: C, 65.91; H, 4.72; F, 12.26; N, 6.78; O, 10.33

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 1673590-38-9 (free base)   2313527-30-7 (sodium)    

Synonym: YUN90389; YUN 90389; YUN-90389; PPARalpha/delta-IN-11; PPARalpha/delta IN 11; PPARalpha/deltaIN11

IUPAC/Chemical Name: 2-(4-Ethoxy-4'-(3-(4-(2-fluorophenyl)-5-oxo-1-(4-(trifluoromethyl)phenyl)-4,5-dihydro-1H-1,2,4-triazol-3-yl)propyl)-[1,1'-biphenyl]-3-yl)acetic acid

InChi Key: YIUSVSPYCXFTHR-UHFFFAOYSA-N

InChi Code: InChI=1S/C34H29F4N3O4/c1-2-45-30-19-14-24(20-25(30)21-32(42)43)23-12-10-22(11-13-23)6-5-9-31-39-41(27-17-15-26(16-18-27)34(36,37)38)33(44)40(31)29-8-4-3-7-28(29)35/h3-4,7-8,10-20H,2,5-6,9,21H2,1H3,(H,42,43)

SMILES Code: O=C(O)CC1=CC(C2=CC=C(CCCC(N3C4=CC=CC=C4F)=NN(C5=CC=C(C(F)(F)F)C=C5)C3=O)C=C2)=CC=C1OCC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 619.6166 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Discovery of potent and selective PPARα​/δ dual antagonists and initial biological studies
Quick View Other Sources
By Jacintho, Jason D.; Baccei, Christopher S.; Bravo, Yalda; Broadhead, Alex; Chen, Austin; Correa, Lucia; Fischer, Kim; Laffitte, Bryan; Lee, Catherine; Lorrain, Daniel S.; et al
From Bioorganic & Medicinal Chemistry Letters (2019), 29(3), 503-508. | Language: English, Database: CAPLUS