PUN30119
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555565

CAS#: 1801530-11-9

Description: PUN30119, also known as Imidazole ketone erastin, is a potent, metabolically stable inhibitor of system xc- and inducer of ferroptosis potentially suitable for in vivo applications. PUN30119 has CAS#1801530-11-9 and Inchi key PSPXJPWGVFNGQI-UHFFFAOYSA-N. According to Hodoodo Chemical Nomenclature, it is temporally named PUN30119 for the convenience of scientific communication.


Price and Availability

Size
Price

500mg
USD 2050
Size
Price

1g
USD 3450
Size
Price

2g
USD 5850

PUN30119, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 555565
Name: PUN30119
CAS#: 1801530-11-9
Chemical Formula: C35H35ClN6O5
Exact Mass: 654.2357
Molecular Weight: 655.152
Elemental Analysis: C, 64.17; H, 5.39; Cl, 5.41; N, 12.83; O, 12.21


Synonym: Imidazole ketone erastin; IKE; Ferroptosis inducer IKE; PUN30119; PUN-30119; PUN 30119;

IUPAC/Chemical Name: 3-(5-(2-(1H-imidazol-1-yl)acetyl)-2-isopropoxyphenyl)-2-((4-(2-(4-chlorophenoxy)acetyl)piperazin-1-yl)methyl)quinazolin-4(3H)-one

InChi Key: PSPXJPWGVFNGQI-UHFFFAOYSA-N

InChi Code: InChI=1S/C35H35ClN6O5/c1-24(2)47-32-12-7-25(31(43)20-40-14-13-37-23-40)19-30(32)42-33(38-29-6-4-3-5-28(29)35(42)45)21-39-15-17-41(18-16-39)34(44)22-46-27-10-8-26(36)9-11-27/h3-14,19,23-24H,15-18,20-22H2,1-2H3

SMILES Code: O=C1N(C2=CC(C(CN3C=NC=C3)=O)=CC=C2OC(C)C)C(CN4CCN(C(COC5=CC=C(Cl)C=C5)=O)CC4)=NC6=C1C=CC=C6


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.90.01


References

1. Zhang Y, et al. Cell Chem Biol. 2019 Jan 31. pii: S2451-9456(19)30030-3.

2. Larraufie MH, et al. Bioorg Med Chem Lett. 2015 Nov 1;25(21):4787-4792.