BUN60856
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555561

CAS#: 959860-85-6

Description: BUN60856, also known as cFMS Receptor Inhibitor II, is a cFMS inhibitor. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

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BUN60856
CAS# 959860-85-6
Instruction

Theoretical Analysis

MedKoo Cat#: 555561
Name: BUN60856
CAS#: 959860-85-6
Chemical Formula: C23H20N4O
Exact Mass: 368.16
Molecular Weight: 368.440
Elemental Analysis: C, 74.98; H, 5.47; N, 15.21; O, 4.34

Price and Availability

Size Price Availability Quantity
200mg USD 1450
500mg USD 2250
1g USD 3850
2g USD 6450
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Synonym: cFMS Receptor Inhibitor II; BUN60856; BUN-60856; BUN 60856;

IUPAC/Chemical Name: 4-[(3,4-Dimethylphenyl)amino]-7-(4-pyridinyl)-3-quinolinecarboxamide

InChi Key: BIICXZWYHQOUEQ-UHFFFAOYSA-N

InChi Code: InChI=1S/C23H20N4O/c1-14-3-5-18(11-15(14)2)27-22-19-6-4-17(16-7-9-25-10-8-16)12-21(19)26-13-20(22)23(24)28/h3-13H,1-2H3,(H2,24,28)(H,26,27)

SMILES Code: O=C(C1=C(NC2=CC=C(C)C(C)=C2)C3=CC=C(C4=CC=NC=C4)C=C3N=C1)N

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info: 1. Compositions and methods for obtaining enriched mesenchymal stem cell cultures. By Short, Brenton John; Duronio, Christopher. From U.S. Pat. Appl. Publ. (2016), US 20160032248 A1 20160204. 2. Preparation of enriched mesenchymal stem cell cultures using CSF1R kinase inhibitors. By Short, Brenton John; Duronio, Christopher. From PCT Int. Appl. (2014), WO 2014138888 A1 20140918. 3. 3D-​QSAR analysis of anilinoquinoline inhibitors of colony stimulating factor-​1 kinase (cFMS)​: implementation of field-​based molecular alignment By Kumari, Archana; Kaur, Maninder; Bahia, Malkeet Singh; Silakari, Om. From Medicinal Chemistry Research (2013), 22(11), 5167-5183. 4. Synthesis of novel anilinoquinolines as c-​fms inhibitors. By Smalley, Terrence L.; Chamberlain, Stanley D.; Mills, Wendy Y.; Musso, David L.; Randhawa, Sab A.; Ray, John A.; Samano, Vicente; Frick, Lloyd. From Bioorganic & Medicinal Chemistry Letters (2007), 17(22), 6257-6260.

Biological target:
In vitro activity:
In vivo activity:

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
Soluble in DMSO 0.0 0.00

Preparing Stock Solutions

The following data is based on the product molecular weight 368.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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